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dc.contributor.authorCombs, Daniel
dc.contributor.authorGoodwin, James L.
dc.contributor.authorQuan, Stuart F.
dc.contributor.authorMorgan, Wayne J.
dc.contributor.authorShetty, Safal
dc.contributor.authorParthasarathy, Sairam
dc.date.accessioned2016-07-19T02:03:00Z
dc.date.available2016-07-19T02:03:00Z
dc.date.issued2016-06-13
dc.identifier.citationInsomnia, Health-Related Quality of Life and Health Outcomes in Children: A Seven Year Longitudinal Cohort 2016, 6:27921 Scientific Reportsen
dc.identifier.issn2045-2322
dc.identifier.doi10.1038/srep27921
dc.identifier.urihttp://hdl.handle.net/10150/617206
dc.description.abstractInsomnia is common in children, and is associated with decreased school performance and increased psychopathology. Although adult insomnia is linked to worsened health-related quality of life (HRQOL), there is insufficient data evaluating insomnia and HRQOL in children. We examined the HRQOL and health associations of insomnia in a longitudinal cohort of 194 children (96 girls, age at study start 8.7 +/- 1.6 years, age at data analysis 15.0 +/- 1.8 years) over 7 years. International Classification of Sleep Disorders, second edition (ICSD2) derived insomnia was seen intermittently in 27% of children, and was persistent in 4%. Children reporting ICSD2-derived insomnia had lower HRQOL. Additionally, the presence of insomnia was associated with an increased risk of reporting a new medical condition (intermittent insomnia odds ratio 5.9 [95% CI 1.3-26.7, p = 0.04], persistent insomnia odds ratio 8 [95% CI 2.3-27.7, p = 0.001]). Persistent ICSD2-derived insomnia was associated with an increased risk of reporting a new medication (odds ratio 4.9 (95% CI 1.0-23.6), p = 0.049), and reporting a new psychiatric medication (odds ratio 13.7, 95% CI: 2.6-73.5, p = 0.002). These associations were present even after adjusting for socioeconomic factors and the presence of obstructive sleep apnea. Insomnia in children is associated with worsened HRQOL and health outcomes.
dc.description.sponsorshipNational Institutes of Health [HL062373, HL095748, HL095799]; PCORI [IHS-1306-2505, 3394]; Arizona Respiratory Center, University of Arizona, Tucson, AZen
dc.language.isoenen
dc.publisherNATURE PUBLISHING GROUPen
dc.relation.urlhttp://www.nature.com/articles/srep27921en
dc.rightsCopyright © The Author(s) 2016. This work is licensed under a Creative Commons Attribution 4.0 International License.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleInsomnia, Health-Related Quality of Life and Health Outcomes in Children: A Seven Year Longitudinal Cohorten
dc.typeArticleen
dc.contributor.departmentUniv Arizona, Dept Pediaten
dc.contributor.departmentUniv Arizona, Dept Meden
dc.contributor.departmentUniv Arizona, Arizona Resp Ctren
dc.contributor.departmentUniv Arizona, Ctr Sleep Disorders,en
dc.contributor.departmentUniv Arizona, Div Pulm Allergy Crit Care & Sleep Meden
dc.identifier.journalScientific Reportsen
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen
refterms.dateFOA2018-09-11T14:35:03Z
html.description.abstractInsomnia is common in children, and is associated with decreased school performance and increased psychopathology. Although adult insomnia is linked to worsened health-related quality of life (HRQOL), there is insufficient data evaluating insomnia and HRQOL in children. We examined the HRQOL and health associations of insomnia in a longitudinal cohort of 194 children (96 girls, age at study start 8.7 +/- 1.6 years, age at data analysis 15.0 +/- 1.8 years) over 7 years. International Classification of Sleep Disorders, second edition (ICSD2) derived insomnia was seen intermittently in 27% of children, and was persistent in 4%. Children reporting ICSD2-derived insomnia had lower HRQOL. Additionally, the presence of insomnia was associated with an increased risk of reporting a new medical condition (intermittent insomnia odds ratio 5.9 [95% CI 1.3-26.7, p = 0.04], persistent insomnia odds ratio 8 [95% CI 2.3-27.7, p = 0.001]). Persistent ICSD2-derived insomnia was associated with an increased risk of reporting a new medication (odds ratio 4.9 (95% CI 1.0-23.6), p = 0.049), and reporting a new psychiatric medication (odds ratio 13.7, 95% CI: 2.6-73.5, p = 0.002). These associations were present even after adjusting for socioeconomic factors and the presence of obstructive sleep apnea. Insomnia in children is associated with worsened HRQOL and health outcomes.


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Copyright © The Author(s) 2016. This work is licensed under a Creative Commons Attribution 4.0 International License.
Except where otherwise noted, this item's license is described as Copyright © The Author(s) 2016. This work is licensed under a Creative Commons Attribution 4.0 International License.