Insomnia, Health-Related Quality of Life and Health Outcomes in Children: A Seven Year Longitudinal Cohort
Goodwin, James L.
Quan, Stuart F.
Morgan, Wayne J.
AffiliationUniv Arizona, Dept Pediat
Univ Arizona, Dept Med
Univ Arizona, Arizona Resp Ctr
Univ Arizona, Ctr Sleep Disorders,
Univ Arizona, Div Pulm Allergy Crit Care & Sleep Med
MetadataShow full item record
PublisherNATURE PUBLISHING GROUP
CitationInsomnia, Health-Related Quality of Life and Health Outcomes in Children: A Seven Year Longitudinal Cohort 2016, 6:27921 Scientific Reports
RightsThis work is licensed under a Creative Commons Attribution 4.0 International License.
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at email@example.com.
AbstractInsomnia is common in children, and is associated with decreased school performance and increased psychopathology. Although adult insomnia is linked to worsened health-related quality of life (HRQOL), there is insufficient data evaluating insomnia and HRQOL in children. We examined the HRQOL and health associations of insomnia in a longitudinal cohort of 194 children (96 girls, age at study start 8.7 +/- 1.6 years, age at data analysis 15.0 +/- 1.8 years) over 7 years. International Classification of Sleep Disorders, second edition (ICSD2) derived insomnia was seen intermittently in 27% of children, and was persistent in 4%. Children reporting ICSD2-derived insomnia had lower HRQOL. Additionally, the presence of insomnia was associated with an increased risk of reporting a new medical condition (intermittent insomnia odds ratio 5.9 [95% CI 1.3-26.7, p = 0.04], persistent insomnia odds ratio 8 [95% CI 2.3-27.7, p = 0.001]). Persistent ICSD2-derived insomnia was associated with an increased risk of reporting a new medication (odds ratio 4.9 (95% CI 1.0-23.6), p = 0.049), and reporting a new psychiatric medication (odds ratio 13.7, 95% CI: 2.6-73.5, p = 0.002). These associations were present even after adjusting for socioeconomic factors and the presence of obstructive sleep apnea. Insomnia in children is associated with worsened HRQOL and health outcomes.
VersionFinal published version
SponsorsNational Institutes of Health [HL062373, HL095748, HL095799]; PCORI [IHS-1306-2505, 3394]; Arizona Respiratory Center, University of Arizona, Tucson, AZ