Small Traditional Human Communities Sustain Genomic Diversity over Microgeographic Scales despite Linguistic Isolation

Persistent Link:
http://hdl.handle.net/10150/620928
Title:
Small Traditional Human Communities Sustain Genomic Diversity over Microgeographic Scales despite Linguistic Isolation
Author:
Cox, Murray P.; Hudjashov, Georgi; Sim, Andre; Savina, Olga; Karafet, Tatiana M.; Sudoyo, Herawati; Lansing, J. Stephen
Affiliation:
Univ Arizona, ARL Div Biotechnol
Issue Date:
2016-06-07
Publisher:
OXFORD UNIV PRESS
Citation:
Mol. Biol. Evol. 33(9):2273–2284 doi:10.1093/molbev/msw099
Journal:
MOLECULAR BIOLOGY AND EVOLUTION
Rights:
© The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/).
Collection Information:
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
Abstract:
At least since the Neolithic, humans have largely lived in networks of small, traditional communities. Often socially isolated, these groups evolved distinct languages and cultures over microgeographic scales of just tens of kilometers. Population genetic theory tells us that genetic drift should act quickly in such isolated groups, thus raising the question: do networks of small human communitiesmaintain levels of genetic diversity over microgeographic scales? This question can no longer be asked in most parts of the world, which have been heavily impacted by historical events that make traditional society structures the exception. However, such studies remain possible in parts of Island Southeast Asia and Oceania, where traditional ways of life are still practiced. We captured genome-wide genetic data, together with linguistic records, for a case-study system-eight villages distributed across Sumba, a small, remote island in eastern Indonesia. More than 4,000 years after these communities were established during the Neolithic period, most speak different languages and can be distinguished genetically. Yet their nuclear diversity is not reduced, instead being comparable to other, evenmuch larger, regional groups. Modeling reveals a separation of time scales: while languages and culture can evolve quickly, creating social barriers, sporadic migration averaged over many generations is sufficient to keep villages linked genetically. This loosely-connected network structure, once the global norm and still extant on Sumba today, provides a living proxy to explore fine-scale genome dynamics in the sort of small traditional communities within which the most recent episodes of human evolution occurred.
Note:
Open access.
ISSN:
0737-4038
PubMed ID:
27274003
DOI:
10.1093/molbev/msw099
Keywords:
genetic diversity; linguistic diversity; gene flow; population structure
Version:
Final published version
Sponsors:
Nanyang Technological University; Singapore Ministry of Education; Royal Society of New Zealand [RDF-10-MAU-001]; NEFREX - European Union [318979]
Additional Links:
http://mbe.oxfordjournals.org/content/33/9/2273

Full metadata record

DC FieldValue Language
dc.contributor.authorCox, Murray P.en
dc.contributor.authorHudjashov, Georgien
dc.contributor.authorSim, Andreen
dc.contributor.authorSavina, Olgaen
dc.contributor.authorKarafet, Tatiana M.en
dc.contributor.authorSudoyo, Herawatien
dc.contributor.authorLansing, J. Stephenen
dc.date.accessioned2016-10-12T00:49:33Z-
dc.date.available2016-10-12T00:49:33Z-
dc.date.issued2016-06-07-
dc.identifier.citationMol. Biol. Evol. 33(9):2273–2284 doi:10.1093/molbev/msw099en
dc.identifier.issn0737-4038-
dc.identifier.pmid27274003-
dc.identifier.doi10.1093/molbev/msw099-
dc.identifier.urihttp://hdl.handle.net/10150/620928-
dc.description.abstractAt least since the Neolithic, humans have largely lived in networks of small, traditional communities. Often socially isolated, these groups evolved distinct languages and cultures over microgeographic scales of just tens of kilometers. Population genetic theory tells us that genetic drift should act quickly in such isolated groups, thus raising the question: do networks of small human communitiesmaintain levels of genetic diversity over microgeographic scales? This question can no longer be asked in most parts of the world, which have been heavily impacted by historical events that make traditional society structures the exception. However, such studies remain possible in parts of Island Southeast Asia and Oceania, where traditional ways of life are still practiced. We captured genome-wide genetic data, together with linguistic records, for a case-study system-eight villages distributed across Sumba, a small, remote island in eastern Indonesia. More than 4,000 years after these communities were established during the Neolithic period, most speak different languages and can be distinguished genetically. Yet their nuclear diversity is not reduced, instead being comparable to other, evenmuch larger, regional groups. Modeling reveals a separation of time scales: while languages and culture can evolve quickly, creating social barriers, sporadic migration averaged over many generations is sufficient to keep villages linked genetically. This loosely-connected network structure, once the global norm and still extant on Sumba today, provides a living proxy to explore fine-scale genome dynamics in the sort of small traditional communities within which the most recent episodes of human evolution occurred.en
dc.description.sponsorshipNanyang Technological University; Singapore Ministry of Education; Royal Society of New Zealand [RDF-10-MAU-001]; NEFREX - European Union [318979]en
dc.language.isoenen
dc.publisherOXFORD UNIV PRESSen
dc.relation.urlhttp://mbe.oxfordjournals.org/content/33/9/2273en
dc.rights© The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/).en
dc.subjectgenetic diversityen
dc.subjectlinguistic diversityen
dc.subjectgene flowen
dc.subjectpopulation structureen
dc.titleSmall Traditional Human Communities Sustain Genomic Diversity over Microgeographic Scales despite Linguistic Isolationen
dc.typeArticleen
dc.contributor.departmentUniv Arizona, ARL Div Biotechnolen
dc.identifier.journalMOLECULAR BIOLOGY AND EVOLUTIONen
dc.description.noteOpen access.en
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen

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