Comparison of Morphine and Fentanyl For Pain Due to Traumatic Injury in the Emergency Department

Persistent Link:
http://hdl.handle.net/10150/614592
Title:
Comparison of Morphine and Fentanyl For Pain Due to Traumatic Injury in the Emergency Department
Author:
Wenderoth, Bradley; Kaneda, Elizabeth; Patanwala, Asad E.
Affiliation:
College of Pharmacy, The University of Arizona
Issue Date:
2011
Rights:
Copyright © is held by the author.
Collection Information:
This item is part of the Pharmacy Student Research Projects collection, made available by the College of Pharmacy and the University Libraries at the University of Arizona. For more information about items in this collection, please contact Jennifer Martin, Associate Librarian and Clinical Instructor, Pharmacy Practice and Science, jenmartin@email.arizona.edu.
Publisher:
The University of Arizona.
Abstract:
OBJECTIVES: To compare fixed equianalgesic doses of morphine and fentanyl with regard to analgesic response for patients who presented to the ED with moderate to severe pain. METHODS: A retrospective cohort study of clinical data obtained through patient medical record review. Median pain reduction on the numeric pain scale was compared between the morphine and fentanyl groups. Independent variables of interest included: Age, sex, weight, initial pain score, injury severity, triage severity and injury type. RESULTS: : Pain scores were reported to be worse in the fentanyl group, p= 0.0002. However pain reduction was similar between the groups; median (IQR) of 2 (1-3) and 2 (1-4) in the morphine and fentanyl groups respectively, p= 0.6707. Injuries were more severe in the fentanyl group; injury severity score (ISS) median (IQR) of 5 (1-9) and 9 (3-12), p=0.0312 and more patients in the fentanyl group required additional opioids within 30 min of their first ED opioid dose, 15 (18%) and 31 (37%), p=0.006. CONCLUSION: Patients in both the morphine and fentanyl groups received similar analgesic response. Patients in the fentanyl group had a higher severity of injury, received higher doses of opioids from the EMS, and required the second dose of opioid sooner than patients in the morphine group.
Description:
Class of 2011 Abstract
Keywords:
MORPHINE; FENTANYL; PAIN; TRAUMATIC INJURY; EMERGENCY DEPARTMENT
Advisor:
Patanwala, Asad E.

Full metadata record

DC FieldValue Language
dc.contributor.advisorPatanwala, Asad E.en
dc.contributor.authorWenderoth, Bradleyen
dc.contributor.authorKaneda, Elizabethen
dc.contributor.authorPatanwala, Asad E.en
dc.date.accessioned2016-06-24T15:50:44Z-
dc.date.available2016-06-24T15:50:44Z-
dc.date.issued2011-
dc.identifier.urihttp://hdl.handle.net/10150/614592-
dc.descriptionClass of 2011 Abstracten
dc.description.abstractOBJECTIVES: To compare fixed equianalgesic doses of morphine and fentanyl with regard to analgesic response for patients who presented to the ED with moderate to severe pain. METHODS: A retrospective cohort study of clinical data obtained through patient medical record review. Median pain reduction on the numeric pain scale was compared between the morphine and fentanyl groups. Independent variables of interest included: Age, sex, weight, initial pain score, injury severity, triage severity and injury type. RESULTS: : Pain scores were reported to be worse in the fentanyl group, p= 0.0002. However pain reduction was similar between the groups; median (IQR) of 2 (1-3) and 2 (1-4) in the morphine and fentanyl groups respectively, p= 0.6707. Injuries were more severe in the fentanyl group; injury severity score (ISS) median (IQR) of 5 (1-9) and 9 (3-12), p=0.0312 and more patients in the fentanyl group required additional opioids within 30 min of their first ED opioid dose, 15 (18%) and 31 (37%), p=0.006. CONCLUSION: Patients in both the morphine and fentanyl groups received similar analgesic response. Patients in the fentanyl group had a higher severity of injury, received higher doses of opioids from the EMS, and required the second dose of opioid sooner than patients in the morphine group.en
dc.language.isoen_USen
dc.publisherThe University of Arizona.en
dc.rightsCopyright © is held by the author.en
dc.subjectMORPHINEen
dc.subjectFENTANYLen
dc.subjectPAINen
dc.subjectTRAUMATIC INJURYen
dc.subjectEMERGENCY DEPARTMENTen
dc.titleComparison of Morphine and Fentanyl For Pain Due to Traumatic Injury in the Emergency Departmenten_US
dc.typetexten
dc.typeElectronic Reporten
dc.contributor.departmentCollege of Pharmacy, The University of Arizonaen
dc.description.collectioninformationThis item is part of the Pharmacy Student Research Projects collection, made available by the College of Pharmacy and the University Libraries at the University of Arizona. For more information about items in this collection, please contact Jennifer Martin, Associate Librarian and Clinical Instructor, Pharmacy Practice and Science, jenmartin@email.arizona.edu.en
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