A Retrospective Evaluation of Eribulin Dosing Schedules in Metastatic Breast Cancer

Persistent Link:
http://hdl.handle.net/10150/613986
Title:
A Retrospective Evaluation of Eribulin Dosing Schedules in Metastatic Breast Cancer
Author:
Gagliardo, Camille; Lybeck, Megan; Bowles, Harmony
Affiliation:
College of Pharmacy, The University of Arizona
Issue Date:
2016
Rights:
Copyright © is held by the author.
Collection Information:
This item is part of the Pharmacy Student Research Projects collection, made available by the College of Pharmacy and the University Libraries at the University of Arizona. For more information about items in this collection, please contact Jennifer Martin, Associate Librarian and Clinical Instructor, Pharmacy Practice and Science, jenmartin@email.arizona.edu.
Publisher:
The University of Arizona.
Abstract:
Objectives: To determine the number of patients treated with eribulin who required an alternate dosing schedule other than “day 1/day 8” due to side effects. Methods: Chart reviews were conducted on all patients who met inclusion criteria. Data collected included patient demographics, history of surgery/radiation, number of past chemotherapy treatments, and lab values prior to each eribulin cycle. Results: A total of 37 patients met inclusion criteria for this study. Ten patients were initially started on the “day 1/day 8” schedule and 3 of those patients required a change to the extended “day 1/day 15” schedule. The remaining 27 patients were started on the extended schedule. Conclusions: The number of patients requiring a dosing schedule change due to side effects was not statistically significant. This finding was due to the fact that the majority of patients were started on an alternate dosing schedule in the beginning of treatment. More extensive studies would be required to determine if a majority of patients would require this alternate dosing schedule, and if this should be initiated in all patients starting on eribulin.
Description:
Class of 2016 Abstract
Keywords:
Retrospective Evaluation; Eribulin; Metastatic; Breast Cancer
Advisor:
Bowles, Harmony

Full metadata record

DC FieldValue Language
dc.contributor.advisorBowles, Harmonyen
dc.contributor.authorGagliardo, Camilleen
dc.contributor.authorLybeck, Meganen
dc.contributor.authorBowles, Harmonyen
dc.date.accessioned2016-06-21T21:19:36Z-
dc.date.available2016-06-21T21:19:36Z-
dc.date.issued2016-
dc.identifier.urihttp://hdl.handle.net/10150/613986-
dc.descriptionClass of 2016 Abstracten
dc.description.abstractObjectives: To determine the number of patients treated with eribulin who required an alternate dosing schedule other than “day 1/day 8” due to side effects. Methods: Chart reviews were conducted on all patients who met inclusion criteria. Data collected included patient demographics, history of surgery/radiation, number of past chemotherapy treatments, and lab values prior to each eribulin cycle. Results: A total of 37 patients met inclusion criteria for this study. Ten patients were initially started on the “day 1/day 8” schedule and 3 of those patients required a change to the extended “day 1/day 15” schedule. The remaining 27 patients were started on the extended schedule. Conclusions: The number of patients requiring a dosing schedule change due to side effects was not statistically significant. This finding was due to the fact that the majority of patients were started on an alternate dosing schedule in the beginning of treatment. More extensive studies would be required to determine if a majority of patients would require this alternate dosing schedule, and if this should be initiated in all patients starting on eribulin.en
dc.language.isoen_USen
dc.publisherThe University of Arizona.en
dc.rightsCopyright © is held by the author.en
dc.subjectRetrospective Evaluationen
dc.subjectEribulinen
dc.subjectMetastaticen
dc.subjectBreast Canceren
dc.titleA Retrospective Evaluation of Eribulin Dosing Schedules in Metastatic Breast Canceren_US
dc.typetexten
dc.typeElectronic Reporten
dc.contributor.departmentCollege of Pharmacy, The University of Arizonaen
dc.description.collectioninformationThis item is part of the Pharmacy Student Research Projects collection, made available by the College of Pharmacy and the University Libraries at the University of Arizona. For more information about items in this collection, please contact Jennifer Martin, Associate Librarian and Clinical Instructor, Pharmacy Practice and Science, jenmartin@email.arizona.edu.en
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