Effectiveness of prophylactic retropharyngeal lymph node irradiation in patients with locally advanced head and neck cancer

Persistent Link:
http://hdl.handle.net/10150/610347
Title:
Effectiveness of prophylactic retropharyngeal lymph node irradiation in patients with locally advanced head and neck cancer
Author:
Nguyen, Nam; Vock, Jacqueline; Vinh-Hung, Vincent; Almeida, Fabio; Ewell, Lars; Betz, Michael; Jang, Siyoung; Vo, Richard; Dutta, Suresh; Godinez, Juan; Karlsson, Ulf; Chi, Alexander
Affiliation:
Department of Radiation Oncology, University of Arizona, Tucson, AZ, USA; Department of Radiation Oncology, University of Bern, Bern, Switzerland, NC, USA; Department of Radiation Oncology, University Hospitals of Geneva, Switzerland, Geneva, USA; University of Galveston Medical School, Galveston, TX, USA; San Antonio Cancer Center, San Antonio, TX, USA; Florida Radiation Oncology Group, Palatka, FL, USA; Marshfield Clinic, Marshfield, WI, USA; Radiation Oncology, University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724-5081, USA; Department of Radiation Oncology, Southwest PET/CT Institute, Tucson, AZ, USA
Issue Date:
2012
Publisher:
BioMed Central
Citation:
Nguyen et al. BMC Cancer 2012, 12:253 http://www.biomedcentral.com/1471-2407/12/253
Journal:
BMC Cancer
Rights:
© 2012 Nguyen et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)
Collection Information:
This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.
Abstract:
BACKGROUND:The aim of the study is to assess the effectiveness of intensity-modulated radiotherapy (IMRT) or image-guided radiotherapy (IGRT) for the prevention of retropharyngeal nodal recurrences in locally advanced head and neck cancer.METHODS:A retrospective review of 76 patients with head and neck cancer undergoing concurrent chemoradiation or postoperative radiotherapy with IMRT or IGRT who were at risk for retropharyngeal nodal recurrences because of anatomic site (hypopharynx, nasopharynx, oropharynx) and/or the presence of nodal metastases was undertaken.The prevalence of retropharyngeal nodal recurrences was assessed on follow-up positron emission tomography (PET)-CT scans.RESULTS:At a median follow-up of 22months (4-53months), no patient developed retropharyngeal nodal recurrences.CONCLUSION:Prophylactic irradiation of retropharyngeal lymph nodes with IMRT or IGRT provides effective regional control for individuals at risk for recurrence in these nodes.
EISSN:
 1471-2407
DOI:
10.1186/1471-2407-12-253
Keywords:
Head and neck cancer; IMRT; IGRT; Retropharyngeal lymph nodes
Version:
Final published version
Additional Links:
http://www.biomedcentral.com/1471-2407/12/253

Full metadata record

DC FieldValue Language
dc.contributor.authorNguyen, Namen
dc.contributor.authorVock, Jacquelineen
dc.contributor.authorVinh-Hung, Vincenten
dc.contributor.authorAlmeida, Fabioen
dc.contributor.authorEwell, Larsen
dc.contributor.authorBetz, Michaelen
dc.contributor.authorJang, Siyoungen
dc.contributor.authorVo, Richarden
dc.contributor.authorDutta, Sureshen
dc.contributor.authorGodinez, Juanen
dc.contributor.authorKarlsson, Ulfen
dc.contributor.authorChi, Alexanderen
dc.date.accessioned2016-05-20T09:04:48Z-
dc.date.available2016-05-20T09:04:48Z-
dc.date.issued2012en
dc.identifier.citationNguyen et al. BMC Cancer 2012, 12:253 http://www.biomedcentral.com/1471-2407/12/253en
dc.identifier.doi10.1186/1471-2407-12-253en
dc.identifier.urihttp://hdl.handle.net/10150/610347-
dc.description.abstractBACKGROUND:The aim of the study is to assess the effectiveness of intensity-modulated radiotherapy (IMRT) or image-guided radiotherapy (IGRT) for the prevention of retropharyngeal nodal recurrences in locally advanced head and neck cancer.METHODS:A retrospective review of 76 patients with head and neck cancer undergoing concurrent chemoradiation or postoperative radiotherapy with IMRT or IGRT who were at risk for retropharyngeal nodal recurrences because of anatomic site (hypopharynx, nasopharynx, oropharynx) and/or the presence of nodal metastases was undertaken.The prevalence of retropharyngeal nodal recurrences was assessed on follow-up positron emission tomography (PET)-CT scans.RESULTS:At a median follow-up of 22months (4-53months), no patient developed retropharyngeal nodal recurrences.CONCLUSION:Prophylactic irradiation of retropharyngeal lymph nodes with IMRT or IGRT provides effective regional control for individuals at risk for recurrence in these nodes.en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urlhttp://www.biomedcentral.com/1471-2407/12/253en
dc.rights© 2012 Nguyen et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)en
dc.subjectHead and neck canceren
dc.subjectIMRTen
dc.subjectIGRTen
dc.subjectRetropharyngeal lymph nodesen
dc.titleEffectiveness of prophylactic retropharyngeal lymph node irradiation in patients with locally advanced head and neck canceren
dc.typeArticleen
dc.identifier.eissn 1471-2407en
dc.contributor.departmentDepartment of Radiation Oncology, University of Arizona, Tucson, AZ, USAen
dc.contributor.departmentDepartment of Radiation Oncology, University of Bern, Bern, Switzerland, NC, USAen
dc.contributor.departmentDepartment of Radiation Oncology, University Hospitals of Geneva, Switzerland, Geneva, USAen
dc.contributor.departmentUniversity of Galveston Medical School, Galveston, TX, USAen
dc.contributor.departmentSan Antonio Cancer Center, San Antonio, TX, USAen
dc.contributor.departmentFlorida Radiation Oncology Group, Palatka, FL, USAen
dc.contributor.departmentMarshfield Clinic, Marshfield, WI, USAen
dc.contributor.departmentRadiation Oncology, University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724-5081, USAen
dc.contributor.departmentDepartment of Radiation Oncology, Southwest PET/CT Institute, Tucson, AZ, USAen
dc.identifier.journalBMC Canceren
dc.description.collectioninformationThis item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen
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