Risk factors associated with lower defecation frequency in hospitalized older adults: a case control study

Persistent Link:
http://hdl.handle.net/10150/610289
Title:
Risk factors associated with lower defecation frequency in hospitalized older adults: a case control study
Author:
Gau, Jen-Tzer; Acharya, Utkarsh H.; Khan, M. Salman; Kao, Tzu-Cheg
Affiliation:
Department of Geriatric Medicine/Gerontology, Ohio University Hertiage College of Osteopathic Medicine; Division of Hematology-Oncology, Department of Internal Medicine, University of Arizona Cancer Center; Division of Pulmonary, Critical Care, Sleep Medicine & Allergy, University of Nebraska Medical Center; Division of Epidemiology and Biostatistics, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences
Issue Date:
2015
Publisher:
BioMed Central Ltd
Citation:
Gau et al. BMC Geriatrics (2015) 15:44 DOI 10.1186/s12877-015-0041-0
Journal:
BMC Geriatrics
Rights:
© 2015 Gau et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
Collection Information:
This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.
Abstract:
BACKGROUND: Constipation is highly prevalent in older adults and may be associated with greater frequency of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We investigated the prevalence of lower defecation frequency (DF) and risk factors (including AECOPD) associated with lower DF among hospitalized elderly patients. METHODS: We conducted a retrospective case-control study in a community hospital of Southeast Ohio. Adults aged 65 years or older admitted during 2004 and 2006 were reviewed (N = 1288). Patients were excluded (N = 212) if their length of stay was less than 3 days, discharge diagnosis of Clostridium difficile-associated diarrhea, death or ventilator- dependent respiratory failure during hospitalization. Lower DF was defined as either an average DF of 0.33 or less per day or no defecation in the first three days of hospitalization; cases (N = 406) and controls (N = 670) were included for the final analysis. RESULTS: Approximately 38% had lower DF in this patient population. Fecal soiling/smearing of at least two episodes was documented in 7% of the patients. With the adjustment of confounders, AECOPD (adjusted odds ratio [AOR] =1.47, 95% confidence interval [CI] =1.01-2.13) and muscle relaxant use (AOR =2.94; 95% CI =1.29-6.69) were significantly associated with lower DF. Supplementation of potassium and antibiotic use prior to hospitalization was associated with lower risk of lower DF. CONCLUSIONS: Approximately 38% of hospitalized older adults had lower DF. AECOPD and use of muscle relaxant were significantly associated with lower DF; while supplementation of potassium and antibiotic use were protective for lower DF risk after adjusting for other variables.
EISSN:
1471-2318
DOI:
10.1186/s12877-015-0041-0
Keywords:
Defecation; Bowel movement; Hospitalized elderly; Acute exacerbation of COPD
Version:
Final published version
Additional Links:
http://www.biomedcentral.com/1471-2318/15/44

Full metadata record

DC FieldValue Language
dc.contributor.authorGau, Jen-Tzeren
dc.contributor.authorAcharya, Utkarsh H.en
dc.contributor.authorKhan, M. Salmanen
dc.contributor.authorKao, Tzu-Chegen
dc.date.accessioned2016-05-20T09:03:21Z-
dc.date.available2016-05-20T09:03:21Z-
dc.date.issued2015en
dc.identifier.citationGau et al. BMC Geriatrics (2015) 15:44 DOI 10.1186/s12877-015-0041-0en
dc.identifier.doi10.1186/s12877-015-0041-0en
dc.identifier.urihttp://hdl.handle.net/10150/610289-
dc.description.abstractBACKGROUND: Constipation is highly prevalent in older adults and may be associated with greater frequency of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We investigated the prevalence of lower defecation frequency (DF) and risk factors (including AECOPD) associated with lower DF among hospitalized elderly patients. METHODS: We conducted a retrospective case-control study in a community hospital of Southeast Ohio. Adults aged 65 years or older admitted during 2004 and 2006 were reviewed (N = 1288). Patients were excluded (N = 212) if their length of stay was less than 3 days, discharge diagnosis of Clostridium difficile-associated diarrhea, death or ventilator- dependent respiratory failure during hospitalization. Lower DF was defined as either an average DF of 0.33 or less per day or no defecation in the first three days of hospitalization; cases (N = 406) and controls (N = 670) were included for the final analysis. RESULTS: Approximately 38% had lower DF in this patient population. Fecal soiling/smearing of at least two episodes was documented in 7% of the patients. With the adjustment of confounders, AECOPD (adjusted odds ratio [AOR] =1.47, 95% confidence interval [CI] =1.01-2.13) and muscle relaxant use (AOR =2.94; 95% CI =1.29-6.69) were significantly associated with lower DF. Supplementation of potassium and antibiotic use prior to hospitalization was associated with lower risk of lower DF. CONCLUSIONS: Approximately 38% of hospitalized older adults had lower DF. AECOPD and use of muscle relaxant were significantly associated with lower DF; while supplementation of potassium and antibiotic use were protective for lower DF risk after adjusting for other variables.en
dc.language.isoenen
dc.publisherBioMed Central Ltden
dc.relation.urlhttp://www.biomedcentral.com/1471-2318/15/44en
dc.rights© 2015 Gau et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)en
dc.subjectDefecationen
dc.subjectBowel movementen
dc.subjectHospitalized elderlyen
dc.subjectAcute exacerbation of COPDen
dc.titleRisk factors associated with lower defecation frequency in hospitalized older adults: a case control studyen
dc.typeArticleen
dc.identifier.eissn1471-2318en
dc.contributor.departmentDepartment of Geriatric Medicine/Gerontology, Ohio University Hertiage College of Osteopathic Medicineen
dc.contributor.departmentDivision of Hematology-Oncology, Department of Internal Medicine, University of Arizona Cancer Centeren
dc.contributor.departmentDivision of Pulmonary, Critical Care, Sleep Medicine & Allergy, University of Nebraska Medical Centeren
dc.contributor.departmentDivision of Epidemiology and Biostatistics, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciencesen
dc.identifier.journalBMC Geriatricsen
dc.description.collectioninformationThis item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen
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