Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing

Persistent Link:
http://hdl.handle.net/10150/610288
Title:
Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing
Author:
Park, Doori; Jung, Je Won; Choi, Beom-Soon; Jayakodi, Murukarthick; Lee, Jeongsoo; Lim, Jongsung; Yu, Yeisoo; Choi, Yong-Soo; Lee, Myeong-Lyeol; Park, Yoonseong; Choi, Ik-Young; Yang, Tae-Jin; Edwards, Owain R.; Nah, Gyoungju; Kwon, Hyung Wook
Affiliation:
Biomodulation Major, Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University; National Instrumentation Center for Environmental Management, College of Agriculture and Life Sciences, Seoul National University; Department of Plant Science, College of Agriculture and Life Sciences, Seoul National University; Arizona Genomics Institute, University of Arizona; National Institute of Agricultural Biotechnology, Rural development Administration; Department of Entomology, Kansas State University; CSIRO Ecosystem Sciences, Centre for Environment and Life Sciences
Issue Date:
2015
Publisher:
BioMed Central Ltd
Citation:
Park et al. BMC Genomics 2015, 16:1 http://www.biomedcentral.com/1471-2164/16/1
Journal:
BMC Genomics
Rights:
© 2015 Park et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
Collection Information:
This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.
Abstract:
BACKGROUND: The honey bee is an important model system for increasing understanding of molecular and neural mechanisms underlying social behaviors relevant to the agricultural industry and basic science. The western honey bee, Apis mellifera, has served as a model species, and its genome sequence has been published. In contrast, the genome of the Asian honey bee, Apis cerana, has not yet been sequenced. A. cerana has been raised in Asian countries for thousands of years and has brought considerable economic benefits to the apicultural industry. A cerana has divergent biological traits compared to A. mellifera and it has played a key role in maintaining biodiversity in eastern and southern Asia. Here we report the first whole genome sequence of A. cerana. RESULTS: Using de novo assembly methods, we produced a 238 Mbp draft of the A. cerana genome and generated 10,651 genes. A.cerana-specific genes were analyzed to better understand the novel characteristics of this honey bee species. Seventy-two percent of the A. cerana-specific genes had more than one GO term, and 1,696 enzymes were categorized into 125 pathways. Genes involved in chemoreception and immunity were carefully identified and compared to those from other sequenced insect models. These included 10 gustatory receptors, 119 odorant receptors, 10 ionotropic receptors, and 160 immune-related genes. CONCLUSIONS: This first report of the whole genome sequence of A. cerana provides resources for comparative sociogenomics, especially in the field of social insect communication. These important tools will contribute to a better understanding of the complex behaviors and natural biology of the Asian honey bee and to anticipate its future evolutionary trajectory.
EISSN:
1471-2164
DOI:
10.1186/1471-2164-16-1
Keywords:
Apis cerana; Asian honey bee; Genome; Social insect; Chemosensory receptors; Honey bee immunity
Version:
Final published version
Additional Links:
http://www.biomedcentral.com/1471-2164/16/1

Full metadata record

DC FieldValue Language
dc.contributor.authorPark, Doorien
dc.contributor.authorJung, Je Wonen
dc.contributor.authorChoi, Beom-Soonen
dc.contributor.authorJayakodi, Murukarthicken
dc.contributor.authorLee, Jeongsooen
dc.contributor.authorLim, Jongsungen
dc.contributor.authorYu, Yeisooen
dc.contributor.authorChoi, Yong-Sooen
dc.contributor.authorLee, Myeong-Lyeolen
dc.contributor.authorPark, Yoonseongen
dc.contributor.authorChoi, Ik-Youngen
dc.contributor.authorYang, Tae-Jinen
dc.contributor.authorEdwards, Owain R.en
dc.contributor.authorNah, Gyoungjuen
dc.contributor.authorKwon, Hyung Wooken
dc.date.accessioned2016-05-20T09:03:19Z-
dc.date.available2016-05-20T09:03:19Z-
dc.date.issued2015en
dc.identifier.citationPark et al. BMC Genomics 2015, 16:1 http://www.biomedcentral.com/1471-2164/16/1en
dc.identifier.doi10.1186/1471-2164-16-1en
dc.identifier.urihttp://hdl.handle.net/10150/610288-
dc.description.abstractBACKGROUND: The honey bee is an important model system for increasing understanding of molecular and neural mechanisms underlying social behaviors relevant to the agricultural industry and basic science. The western honey bee, Apis mellifera, has served as a model species, and its genome sequence has been published. In contrast, the genome of the Asian honey bee, Apis cerana, has not yet been sequenced. A. cerana has been raised in Asian countries for thousands of years and has brought considerable economic benefits to the apicultural industry. A cerana has divergent biological traits compared to A. mellifera and it has played a key role in maintaining biodiversity in eastern and southern Asia. Here we report the first whole genome sequence of A. cerana. RESULTS: Using de novo assembly methods, we produced a 238 Mbp draft of the A. cerana genome and generated 10,651 genes. A.cerana-specific genes were analyzed to better understand the novel characteristics of this honey bee species. Seventy-two percent of the A. cerana-specific genes had more than one GO term, and 1,696 enzymes were categorized into 125 pathways. Genes involved in chemoreception and immunity were carefully identified and compared to those from other sequenced insect models. These included 10 gustatory receptors, 119 odorant receptors, 10 ionotropic receptors, and 160 immune-related genes. CONCLUSIONS: This first report of the whole genome sequence of A. cerana provides resources for comparative sociogenomics, especially in the field of social insect communication. These important tools will contribute to a better understanding of the complex behaviors and natural biology of the Asian honey bee and to anticipate its future evolutionary trajectory.en
dc.language.isoenen
dc.publisherBioMed Central Ltden
dc.relation.urlhttp://www.biomedcentral.com/1471-2164/16/1en
dc.rights© 2015 Park et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)en
dc.subjectApis ceranaen
dc.subjectAsian honey beeen
dc.subjectGenomeen
dc.subjectSocial insecten
dc.subjectChemosensory receptorsen
dc.subjectHoney bee immunityen
dc.titleUncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencingen
dc.typeArticleen
dc.identifier.eissn1471-2164en
dc.contributor.departmentBiomodulation Major, Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National Universityen
dc.contributor.departmentNational Instrumentation Center for Environmental Management, College of Agriculture and Life Sciences, Seoul National Universityen
dc.contributor.departmentDepartment of Plant Science, College of Agriculture and Life Sciences, Seoul National Universityen
dc.contributor.departmentArizona Genomics Institute, University of Arizonaen
dc.contributor.departmentNational Institute of Agricultural Biotechnology, Rural development Administrationen
dc.contributor.departmentDepartment of Entomology, Kansas State Universityen
dc.contributor.departmentCSIRO Ecosystem Sciences, Centre for Environment and Life Sciencesen
dc.identifier.journalBMC Genomicsen
dc.description.collectioninformationThis item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen
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