Predictors of cardiopulmonary arrest outcome in a comprehensive cancer center intensive care unit

Persistent Link:
http://hdl.handle.net/10150/610246
Title:
Predictors of cardiopulmonary arrest outcome in a comprehensive cancer center intensive care unit
Author:
Khasawneh, Faisal; Kamel, Mahmoud; Abu-Zaid, Mohammad
Affiliation:
Section of Critical Care Medicine, Department of Internal Medicine, School of Medicine, Texas Tech University Health Sciences Center, 1400 S. Coulter Street, Amarillo, Texas, 79106, USA; Department of Internal Medicine, School of Medicine, University of Arizona, Tucson, AZ, USA
Issue Date:
2013
Publisher:
BioMed Central
Citation:
Khasawneh et al. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2013, 21:18 http://www.sjtrem.com/content/21/1/18
Journal:
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Rights:
© 2013 Khasawneh et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)
Collection Information:
This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.
Abstract:
BACKGROUND:Some comprehensive cancer centers in industrialized countries have reported improved outcomes in their cardiopulmonary arrest (CPA) patients. Little is known about the outcomes and predictors of CPA in cancer centers in other parts of the world. The objective of this study was to examine the predictors of CPA outcome in a comprehensive cancer center closed medical-surgical intensive care unit (ICU) located in Amman, Jordan.METHODS:In this retrospective single-center cohort study, we identified 104 patients who had a CPA during their stay in the ICU between 1/1/2008 and 6/30/2009. Demographic data and CPA-related variables and outcome were extracted from medical records. Comparisons between different variables and CPA outcome were conducted using logistic regression.RESULTS:The mean age of the group was 49.7+/-15.3years. The mean APACHE II score was 23.7+/-8.0. Thirty six patients (34.6%) were resuscitated successfully but 8 of them (7.7% of the cohort) left the ICU alive and only 6 out of the 8 (5.8% of the cohort) left the hospital alive. The following variables predict resuscitation failure: acute kidney injury (OR 1.7, CI: 1.1 - 2.6), being on mechanical ventilation (OR 3.8, CI: 1.3 - 11), refractory shock (OR 4.7, CI: 1.8 - 12) and CPR duration (OR 1.1, CI: 1.1 - 1.2).CONCLUSION:Survival among cancer patients who develop CPA in the ICU continues to be poor. Once cancer patients suffered a CPA in the ICU multiple factors predicted resuscitation failure but CPR duration was the only factor that predicted resuscitation failure and ICU as well as hospital mortality.
EISSN:
1757-7241
DOI:
10.1186/1757-7241-21-18
Keywords:
Cardiopulmonary arrest; Critically-ill cancer patients; Outcome predictors
Version:
Final published version
Additional Links:
http://www.sjtrem.com/content/21/1/18

Full metadata record

DC FieldValue Language
dc.contributor.authorKhasawneh, Faisalen
dc.contributor.authorKamel, Mahmouden
dc.contributor.authorAbu-Zaid, Mohammaden
dc.date.accessioned2016-05-20T09:02:06Z-
dc.date.available2016-05-20T09:02:06Z-
dc.date.issued2013en
dc.identifier.citationKhasawneh et al. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2013, 21:18 http://www.sjtrem.com/content/21/1/18en
dc.identifier.doi10.1186/1757-7241-21-18en
dc.identifier.urihttp://hdl.handle.net/10150/610246-
dc.description.abstractBACKGROUND:Some comprehensive cancer centers in industrialized countries have reported improved outcomes in their cardiopulmonary arrest (CPA) patients. Little is known about the outcomes and predictors of CPA in cancer centers in other parts of the world. The objective of this study was to examine the predictors of CPA outcome in a comprehensive cancer center closed medical-surgical intensive care unit (ICU) located in Amman, Jordan.METHODS:In this retrospective single-center cohort study, we identified 104 patients who had a CPA during their stay in the ICU between 1/1/2008 and 6/30/2009. Demographic data and CPA-related variables and outcome were extracted from medical records. Comparisons between different variables and CPA outcome were conducted using logistic regression.RESULTS:The mean age of the group was 49.7+/-15.3years. The mean APACHE II score was 23.7+/-8.0. Thirty six patients (34.6%) were resuscitated successfully but 8 of them (7.7% of the cohort) left the ICU alive and only 6 out of the 8 (5.8% of the cohort) left the hospital alive. The following variables predict resuscitation failure: acute kidney injury (OR 1.7, CI: 1.1 - 2.6), being on mechanical ventilation (OR 3.8, CI: 1.3 - 11), refractory shock (OR 4.7, CI: 1.8 - 12) and CPR duration (OR 1.1, CI: 1.1 - 1.2).CONCLUSION:Survival among cancer patients who develop CPA in the ICU continues to be poor. Once cancer patients suffered a CPA in the ICU multiple factors predicted resuscitation failure but CPR duration was the only factor that predicted resuscitation failure and ICU as well as hospital mortality.en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urlhttp://www.sjtrem.com/content/21/1/18en
dc.rights© 2013 Khasawneh et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)en
dc.subjectCardiopulmonary arresten
dc.subjectCritically-ill cancer patientsen
dc.subjectOutcome predictorsen
dc.titlePredictors of cardiopulmonary arrest outcome in a comprehensive cancer center intensive care uniten
dc.typeArticleen
dc.identifier.eissn1757-7241en
dc.contributor.departmentSection of Critical Care Medicine, Department of Internal Medicine, School of Medicine, Texas Tech University Health Sciences Center, 1400 S. Coulter Street, Amarillo, Texas, 79106, USAen
dc.contributor.departmentDepartment of Internal Medicine, School of Medicine, University of Arizona, Tucson, AZ, USAen
dc.identifier.journalScandinavian Journal of Trauma, Resuscitation and Emergency Medicineen
dc.description.collectioninformationThis item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen
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