Phantom investigation of 3D motion-dependent volume aliasing during CT simulation for radiation therapy planning

Persistent Link:
http://hdl.handle.net/10150/610239
Title:
Phantom investigation of 3D motion-dependent volume aliasing during CT simulation for radiation therapy planning
Author:
Tanyi, James; Fuss, Martin; Varchena, Vladimir; Lancaster, Jack; Salter, Bill
Affiliation:
Department of Radiation Oncology, University of Arizona Health Science Center, Tucson, AZ 85724, USA; Department of Radiation Oncology and Radiation Medicine, Oregon Health and Science University, Portland, OR 97239, USA; Department of Radiation Oncology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA; Computerized Imaging Reference Systems (CIRS), Incorporated, Norfolk, VA 23513, USA; Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, TX 78284, USA; Department of Radiation Oncology, University of Utah/Huntsman Cancer Institute, Salt Lake City, UT 84112, USA
Issue Date:
2007
Publisher:
BioMed Central
Citation:
Radiation Oncology 2007, 2:10 doi:10.1186/1748-717X-2-10
Journal:
Radiation Oncology
Rights:
© 2007 Tanyi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)
Collection Information:
This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.
Abstract:
PURPOSE:To quantify volumetric and positional aliasing during non-gated fast- and slow-scan acquisition CT in the presence of 3D target motion.METHODS:Single-slice fast, single-slice slow, and multi-slice fast scan helical CTs were acquired of dynamic spherical targets (1 and 3.15 cm in diameter), embedded in an anthropomorphic phantom. 3D target motions typical of clinically observed tumor motion parameters were investigated. Motion excursions included +/- 5, +/- 10, and +/- 15 mm displacements in the S-I direction synchronized with constant displacements of +/- 5 and +/- 2 mm in the A-P and lateral directions, respectively. For each target, scan technique, and motion excursion, eight different initial motion-to-scan phase relationships were investigated.RESULTS:An anticipated general trend of target volume overestimation was observed. The mean percentage overestimation of the true physical target volume typically increased with target motion amplitude and decreasing target diameter. Slow-scan percentage overestimations were larger, and better approximated the time-averaged motion envelope, as opposed to fast-scans. Motion induced centroid misrepresentation was greater in the S-I direction for fast-scan techniques, and transaxial direction for the slow-scan technique. Overestimation is fairly uniform for slice widths < 5 mm, beyond which there is gross overestimation.CONCLUSION:Non-gated CT imaging of targets describing clinically relevant, 3D motion results in aliased overestimation of the target volume and misrepresentation of centroid location, with little or no correlation between the physical target geometry and the CT-generated target geometry. Slow-scan techniques are a practical method for characterizing time-averaged target position. Fast-scan techniques provide a more reliable, albeit still distorted, target margin.
EISSN:
1748-717X
DOI:
10.1186/1748-717X-2-10
Version:
Final published version
Additional Links:
http://www.ro-journal.com/content/2/1/10

Full metadata record

DC FieldValue Language
dc.contributor.authorTanyi, Jamesen
dc.contributor.authorFuss, Martinen
dc.contributor.authorVarchena, Vladimiren
dc.contributor.authorLancaster, Jacken
dc.contributor.authorSalter, Billen
dc.date.accessioned2016-05-20T09:01:55Z-
dc.date.available2016-05-20T09:01:55Z-
dc.date.issued2007en
dc.identifier.citationRadiation Oncology 2007, 2:10 doi:10.1186/1748-717X-2-10en
dc.identifier.doi10.1186/1748-717X-2-10en
dc.identifier.urihttp://hdl.handle.net/10150/610239-
dc.description.abstractPURPOSE:To quantify volumetric and positional aliasing during non-gated fast- and slow-scan acquisition CT in the presence of 3D target motion.METHODS:Single-slice fast, single-slice slow, and multi-slice fast scan helical CTs were acquired of dynamic spherical targets (1 and 3.15 cm in diameter), embedded in an anthropomorphic phantom. 3D target motions typical of clinically observed tumor motion parameters were investigated. Motion excursions included +/- 5, +/- 10, and +/- 15 mm displacements in the S-I direction synchronized with constant displacements of +/- 5 and +/- 2 mm in the A-P and lateral directions, respectively. For each target, scan technique, and motion excursion, eight different initial motion-to-scan phase relationships were investigated.RESULTS:An anticipated general trend of target volume overestimation was observed. The mean percentage overestimation of the true physical target volume typically increased with target motion amplitude and decreasing target diameter. Slow-scan percentage overestimations were larger, and better approximated the time-averaged motion envelope, as opposed to fast-scans. Motion induced centroid misrepresentation was greater in the S-I direction for fast-scan techniques, and transaxial direction for the slow-scan technique. Overestimation is fairly uniform for slice widths < 5 mm, beyond which there is gross overestimation.CONCLUSION:Non-gated CT imaging of targets describing clinically relevant, 3D motion results in aliased overestimation of the target volume and misrepresentation of centroid location, with little or no correlation between the physical target geometry and the CT-generated target geometry. Slow-scan techniques are a practical method for characterizing time-averaged target position. Fast-scan techniques provide a more reliable, albeit still distorted, target margin.en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urlhttp://www.ro-journal.com/content/2/1/10en
dc.rights© 2007 Tanyi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)en
dc.titlePhantom investigation of 3D motion-dependent volume aliasing during CT simulation for radiation therapy planningen
dc.typeArticleen
dc.identifier.eissn1748-717Xen
dc.contributor.departmentDepartment of Radiation Oncology, University of Arizona Health Science Center, Tucson, AZ 85724, USAen
dc.contributor.departmentDepartment of Radiation Oncology and Radiation Medicine, Oregon Health and Science University, Portland, OR 97239, USAen
dc.contributor.departmentDepartment of Radiation Oncology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USAen
dc.contributor.departmentComputerized Imaging Reference Systems (CIRS), Incorporated, Norfolk, VA 23513, USAen
dc.contributor.departmentResearch Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, TX 78284, USAen
dc.contributor.departmentDepartment of Radiation Oncology, University of Utah/Huntsman Cancer Institute, Salt Lake City, UT 84112, USAen
dc.identifier.journalRadiation Oncologyen
dc.description.collectioninformationThis item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen
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