Virulence of mixed fungal infections in honey bee brood

Persistent Link:
http://hdl.handle.net/10150/610138
Title:
Virulence of mixed fungal infections in honey bee brood
Author:
Vojvodic, Svjetlana; Boomsma, Jacobus; Eilenberg, Jorgen; Jensen, Annette
Affiliation:
Center for Social Evolution, Department of Agriculture and Ecology Faculty of Life Sciences, University of Copenhagen, Thorvaldsensvej 40, DK 1871 Frederiksberg C, Denmark; Current address: Center for Insect Science, University of Arizona 1007 E. Lowell Street, P.O. Box 210106, Tucson AZ 85721-0106, USA; Centre for Social Evolution, Department of Biology, University of Copenhagen, Universitetsparken 15, 2100 Copenhagen, Denmark
Issue Date:
2012
Publisher:
BioMed Central
Citation:
Vojvodic et al. Frontiers in Zoology 2012, 9:5 http://www.frontiersinzoology.com/content/9/1/5
Journal:
Frontiers in Zoology
Rights:
© 2012 Vojvodic et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)
Collection Information:
This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.
Abstract:
INTRODUCTION:Honey bees, Apis mellifera, have a diverse community of pathogens. Previous research has mostly focused on bacterial brood diseases of high virulence, but milder diseases caused by fungal pathogens have recently attracted more attention. This interest has been triggered by partial evidence that co-infection with multiple pathogens has the potential to accelerate honey bee mortality. In the present study we tested whether co-infection with closely related fungal brood-pathogen species that are either specialists or non-specialist results in higher host mortality than infections with a single specialist. We used a specially designed laboratory assay to expose honey bee larvae to controlled infections with spores of three Ascosphaera species: A. apis, the specialist pathogen that causes chalkbrood disease in honey bees, A. proliperda, a specialist pathogen that causes chalkbrood disease in solitary bees, and A. atra, a saprophytic fungus growing typically on pollen brood-provision masses of solitary bees.RESULTS:We show for the first time that single infection with a pollen fungus A. atra may induce some mortality and that co-infection with A. atra and A. apis resulted in higher mortality of honey bees compared to single infections with A. apis. However, similar single and mixed infections with A. proliperda did not increase brood mortality.CONCLUSION:Our results show that co-infection with a closely related fungal species can either increase or have no effect on host mortality, depending on the identity of the second species. Together with other studies suggesting that multiple interacting pathogens may be contributing to worldwide honey bee health declines, our results highlight the importance of studying effects of multiple infections, even when all interacting species are not known to be specialist pathogens.
EISSN:
1742-9994
DOI:
10.1186/1742-9994-9-5
Keywords:
Apis mellifera; Ascosphaera; Competition; Mixed infections; Virulence
Version:
Final published version
Additional Links:
http://www.frontiersinzoology.com/content/9/1/5

Full metadata record

DC FieldValue Language
dc.contributor.authorVojvodic, Svjetlanaen
dc.contributor.authorBoomsma, Jacobusen
dc.contributor.authorEilenberg, Jorgenen
dc.contributor.authorJensen, Annetteen
dc.date.accessioned2016-05-20T08:59:25Z-
dc.date.available2016-05-20T08:59:25Z-
dc.date.issued2012en
dc.identifier.citationVojvodic et al. Frontiers in Zoology 2012, 9:5 http://www.frontiersinzoology.com/content/9/1/5en
dc.identifier.doi10.1186/1742-9994-9-5en
dc.identifier.urihttp://hdl.handle.net/10150/610138-
dc.description.abstractINTRODUCTION:Honey bees, Apis mellifera, have a diverse community of pathogens. Previous research has mostly focused on bacterial brood diseases of high virulence, but milder diseases caused by fungal pathogens have recently attracted more attention. This interest has been triggered by partial evidence that co-infection with multiple pathogens has the potential to accelerate honey bee mortality. In the present study we tested whether co-infection with closely related fungal brood-pathogen species that are either specialists or non-specialist results in higher host mortality than infections with a single specialist. We used a specially designed laboratory assay to expose honey bee larvae to controlled infections with spores of three Ascosphaera species: A. apis, the specialist pathogen that causes chalkbrood disease in honey bees, A. proliperda, a specialist pathogen that causes chalkbrood disease in solitary bees, and A. atra, a saprophytic fungus growing typically on pollen brood-provision masses of solitary bees.RESULTS:We show for the first time that single infection with a pollen fungus A. atra may induce some mortality and that co-infection with A. atra and A. apis resulted in higher mortality of honey bees compared to single infections with A. apis. However, similar single and mixed infections with A. proliperda did not increase brood mortality.CONCLUSION:Our results show that co-infection with a closely related fungal species can either increase or have no effect on host mortality, depending on the identity of the second species. Together with other studies suggesting that multiple interacting pathogens may be contributing to worldwide honey bee health declines, our results highlight the importance of studying effects of multiple infections, even when all interacting species are not known to be specialist pathogens.en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urlhttp://www.frontiersinzoology.com/content/9/1/5en
dc.rights© 2012 Vojvodic et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)en
dc.subjectApis melliferaen
dc.subjectAscosphaeraen
dc.subjectCompetitionen
dc.subjectMixed infectionsen
dc.subjectVirulenceen
dc.titleVirulence of mixed fungal infections in honey bee brooden
dc.typeArticleen
dc.identifier.eissn1742-9994en
dc.contributor.departmentCenter for Social Evolution, Department of Agriculture and Ecology Faculty of Life Sciences, University of Copenhagen, Thorvaldsensvej 40, DK 1871 Frederiksberg C, Denmarken
dc.contributor.departmentCurrent address: Center for Insect Science, University of Arizona 1007 E. Lowell Street, P.O. Box 210106, Tucson AZ 85721-0106, USAen
dc.contributor.departmentCentre for Social Evolution, Department of Biology, University of Copenhagen, Universitetsparken 15, 2100 Copenhagen, Denmarken
dc.identifier.journalFrontiers in Zoologyen
dc.description.collectioninformationThis item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen
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