Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial

Persistent Link:
http://hdl.handle.net/10150/610092
Title:
Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial
Author:
Breitborde, Nicholas; Moreno, Francisco; Mai-Dixon, Natalie; Peterson, Rachele; Durst, Linda; Bernstein, Beth; Byreddy, Seenaiah; McFarlane, William
Affiliation:
Department of Psychiatry, University of Arizona, 1501 N. Campbell Ave., PO Box 245002, Tucson, AZ, 85724-5002, USA; Department of Psychiatry, University Physicians Hospital, 2800 E. Ajo Way, Tucson, Arizona, 85713, USA; Department of Psychiatry, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, New York, 14642, USA; Department of Psychiatry, Maine Medical Center, 295 Park Ave., Portland, Maine, 04102, USA
Issue Date:
2011
Publisher:
BioMed Central
Citation:
Breitborde et al. BMC Psychiatry 2011, 11:9 http://www.biomedcentral.com/1471-244X/11/9
Journal:
BMC Psychiatry
Rights:
© 2011 Breitborde et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)
Collection Information:
This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.
Abstract:
BACKGROUND:Multifamily group psychoeducation (MFG) has been shown to reduce relapse rates among individuals with first-episode psychosis. However, given the cognitive demands associated with participating in this intervention (e.g., learning and applying a structured problem-solving activity), the cognitive deficits that accompany psychotic disorders may limit the ability of certain individuals to benefit from this intervention. Thus, the goal of this study is to examine whether individuals with first-episode psychosis who participate simultaneously in MFG and cognitive remediation--an intervention shown to improve cognitive functioning among individuals with psychotic disorders--will be less likely to experience a relapse than individuals who participate in MFG alone.METHODS/DESIGN:Forty individuals with first-episode psychosis and their caregiving relative will be recruited to participate in this study. Individuals with first-episode psychosis will be randomized to one of two conditions: (i) MFG with concurrent participation in cognitive remediation or (ii) MFG alone. The primary outcome for this study is relapse of psychotic symptoms. We will also examine secondary outcomes among both individuals with first-episode psychosis (i.e., social and vocational functioning, health-related quality of life, service utilization, independent living status, and cognitive functioning) and their caregiving relatives (i.e., caregiver burden, anxiety, and depression)DISCUSSION:Cognitive remediation offers the possibility of ameliorating a specific deficit (i.e., deficits in cognitive functioning) that often accompanies psychotic symptoms and may restrict the magnitude of the clinical benefits derived from MFG.TRIAL REGISTRATION:ClinicalTrials (NCT): NCT01196286
EISSN:
1471-244X
DOI:
10.1186/1471-244X-11-9
Version:
Final published version
Additional Links:
http://www.biomedcentral.com/1471-244X/11/9

Full metadata record

DC FieldValue Language
dc.contributor.authorBreitborde, Nicholasen
dc.contributor.authorMoreno, Franciscoen
dc.contributor.authorMai-Dixon, Natalieen
dc.contributor.authorPeterson, Racheleen
dc.contributor.authorDurst, Lindaen
dc.contributor.authorBernstein, Bethen
dc.contributor.authorByreddy, Seenaiahen
dc.contributor.authorMcFarlane, Williamen
dc.date.accessioned2016-05-20T08:58:22Z-
dc.date.available2016-05-20T08:58:22Z-
dc.date.issued2011en
dc.identifier.citationBreitborde et al. BMC Psychiatry 2011, 11:9 http://www.biomedcentral.com/1471-244X/11/9en
dc.identifier.doi10.1186/1471-244X-11-9en
dc.identifier.urihttp://hdl.handle.net/10150/610092-
dc.description.abstractBACKGROUND:Multifamily group psychoeducation (MFG) has been shown to reduce relapse rates among individuals with first-episode psychosis. However, given the cognitive demands associated with participating in this intervention (e.g., learning and applying a structured problem-solving activity), the cognitive deficits that accompany psychotic disorders may limit the ability of certain individuals to benefit from this intervention. Thus, the goal of this study is to examine whether individuals with first-episode psychosis who participate simultaneously in MFG and cognitive remediation--an intervention shown to improve cognitive functioning among individuals with psychotic disorders--will be less likely to experience a relapse than individuals who participate in MFG alone.METHODS/DESIGN:Forty individuals with first-episode psychosis and their caregiving relative will be recruited to participate in this study. Individuals with first-episode psychosis will be randomized to one of two conditions: (i) MFG with concurrent participation in cognitive remediation or (ii) MFG alone. The primary outcome for this study is relapse of psychotic symptoms. We will also examine secondary outcomes among both individuals with first-episode psychosis (i.e., social and vocational functioning, health-related quality of life, service utilization, independent living status, and cognitive functioning) and their caregiving relatives (i.e., caregiver burden, anxiety, and depression)DISCUSSION:Cognitive remediation offers the possibility of ameliorating a specific deficit (i.e., deficits in cognitive functioning) that often accompanies psychotic symptoms and may restrict the magnitude of the clinical benefits derived from MFG.TRIAL REGISTRATION:ClinicalTrials (NCT): NCT01196286en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urlhttp://www.biomedcentral.com/1471-244X/11/9en
dc.rights© 2011 Breitborde et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0)en
dc.titleMultifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trialen
dc.typeArticleen
dc.identifier.eissn1471-244Xen
dc.contributor.departmentDepartment of Psychiatry, University of Arizona, 1501 N. Campbell Ave., PO Box 245002, Tucson, AZ, 85724-5002, USAen
dc.contributor.departmentDepartment of Psychiatry, University Physicians Hospital, 2800 E. Ajo Way, Tucson, Arizona, 85713, USAen
dc.contributor.departmentDepartment of Psychiatry, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, New York, 14642, USAen
dc.contributor.departmentDepartment of Psychiatry, Maine Medical Center, 295 Park Ave., Portland, Maine, 04102, USAen
dc.identifier.journalBMC Psychiatryen
dc.description.collectioninformationThis item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at repository@u.library.arizona.edu.en
dc.eprint.versionFinal published versionen
All Items in UA Campus Repository are protected by copyright, with all rights reserved, unless otherwise indicated.