Neonatal Necrotizing Enterocolitis and the Clinical Applications of Bile Acids in Prevention of the Disease

Persistent Link:
http://hdl.handle.net/10150/579407
Title:
Neonatal Necrotizing Enterocolitis and the Clinical Applications of Bile Acids in Prevention of the Disease
Author:
Romo, Ryan Elisabeth
Issue Date:
2015
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Neonatal necrotizing enterocolitis (NEC) is the gastrointestinal disease responsible for the most deaths of premature infants. This honors thesis looks at the role of bile acids in NEC through analyzing bile acid concentration in neonatal stool samples. Subjects were enrolled from the neonatal intensive care unit at the Banner University Medical Center in Tucson, Arizona, their fecal samples were collected and then analyzed using Diazyme Total Bile Acids Assay Kit. There was a statistically significant difference in coefficients of variation between infants with and without NEC, suggesting that bile acid levels could be used clinically to predict the onset of NEC so that changes can be made to prevent the progression of the disease.
Type:
text; Electronic Thesis
Degree Name:
B.S.H.S.
Degree Level:
bachelors
Degree Program:
Honors College; Physiology
Degree Grantor:
University of Arizona
Advisor:
Halpern, Melissa

Full metadata record

DC FieldValue Language
dc.language.isoen_USen
dc.titleNeonatal Necrotizing Enterocolitis and the Clinical Applications of Bile Acids in Prevention of the Diseaseen_US
dc.contributor.authorRomo, Ryan Elisabethen
dc.date.issued2015en
dc.publisherThe University of Arizona.en
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en
dc.description.abstractNeonatal necrotizing enterocolitis (NEC) is the gastrointestinal disease responsible for the most deaths of premature infants. This honors thesis looks at the role of bile acids in NEC through analyzing bile acid concentration in neonatal stool samples. Subjects were enrolled from the neonatal intensive care unit at the Banner University Medical Center in Tucson, Arizona, their fecal samples were collected and then analyzed using Diazyme Total Bile Acids Assay Kit. There was a statistically significant difference in coefficients of variation between infants with and without NEC, suggesting that bile acid levels could be used clinically to predict the onset of NEC so that changes can be made to prevent the progression of the disease.en
dc.typetexten
dc.typeElectronic Thesisen
thesis.degree.nameB.S.H.S.en
thesis.degree.levelbachelorsen
thesis.degree.disciplineHonors Collegeen
thesis.degree.disciplinePhysiologyen
thesis.degree.grantorUniversity of Arizonaen
dc.contributor.advisorHalpern, Melissaen
All Items in UA Campus Repository are protected by copyright, with all rights reserved, unless otherwise indicated.