INTERCHANGEABILITY OF THE I‐STAT POINT OF CARE ANALYZER WITH CENTRAL LABORATORY TESTING IN AN EMERGENCY DEPARTMENT SETTING

Persistent Link:
http://hdl.handle.net/10150/528208
Title:
INTERCHANGEABILITY OF THE I‐STAT POINT OF CARE ANALYZER WITH CENTRAL LABORATORY TESTING IN AN EMERGENCY DEPARTMENT SETTING
Author:
Little, Colin
Affiliation:
The University of Arizona College of Medicine - Phoenix
Issue Date:
10-Apr-2015
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the College of Medicine - Phoenix, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Collection Information:
This item is part of the College of Medicine - Phoenix Scholarly Projects 2015 collection. For more information, contact the Phoenix Biomedical Campus Library at pbc-library@email.arizona.edu.
Publisher:
The University of Arizona.
Abstract:
Background and Significance: The i‐STAT point of care blood analyzer is a handheld device used for a variety of laboratory analyses in medical settings. Much research has been performed to evaluate its validity, but it has not been exhaustively tested in real‐world emergency department settings, despite its increasingly popular use in such settings. Methods: We retrospectively examined medical records at the Maricopa Integrated Health Systems Emergency Department to find 100 instances between February 2014 and September 2014 in which a patient had electrolyte testing performed on both the i‐STAT and in the central laboratory within a 60 minute timeframe. These data were examined using variance of means and Bland‐Altman graphing for equivalency. Results: We set the clinical equivalence threshold for each lab to be 5% of the mean normal value. That is, if the i‐STAT differed from central lab by less than 5% of the middle of the normal range (137‐145 for sodium, 5% of which is 7) then we consider them to be clinically equivalent. At this level we were unable to show clinical equivalence. In additional, all electrolytes tested showed small but significant bias between the i‐STAT and the central laboratory. Re‐examination of the data excluding all measurements more than 15 minutes apart showed similar findings. Conclusions: At this time we cannot show equivalency between the i‐STAT device and the central laboratory when used under real‐life emergency department conditions. More research is needed is to support or refute these findings.
Keywords:
I-Stat; Blood Analyzer; Emergency Department
MeSH Subjects:
Emergency Service, Hospital; Laboratories
Description:
A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.
Mentor:
Sarko, John MD

Full metadata record

DC FieldValue Language
dc.language.isoen_USen
dc.titleINTERCHANGEABILITY OF THE I‐STAT POINT OF CARE ANALYZER WITH CENTRAL LABORATORY TESTING IN AN EMERGENCY DEPARTMENT SETTINGen_US
dc.contributor.authorLittle, Colinen
dc.contributor.departmentThe University of Arizona College of Medicine - Phoenixen
dc.date.issued2015-04-10en
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the College of Medicine - Phoenix, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en
dc.description.collectioninformationThis item is part of the College of Medicine - Phoenix Scholarly Projects 2015 collection. For more information, contact the Phoenix Biomedical Campus Library at pbc-library@email.arizona.edu.en
dc.publisherThe University of Arizona.en
dc.description.abstractBackground and Significance: The i‐STAT point of care blood analyzer is a handheld device used for a variety of laboratory analyses in medical settings. Much research has been performed to evaluate its validity, but it has not been exhaustively tested in real‐world emergency department settings, despite its increasingly popular use in such settings. Methods: We retrospectively examined medical records at the Maricopa Integrated Health Systems Emergency Department to find 100 instances between February 2014 and September 2014 in which a patient had electrolyte testing performed on both the i‐STAT and in the central laboratory within a 60 minute timeframe. These data were examined using variance of means and Bland‐Altman graphing for equivalency. Results: We set the clinical equivalence threshold for each lab to be 5% of the mean normal value. That is, if the i‐STAT differed from central lab by less than 5% of the middle of the normal range (137‐145 for sodium, 5% of which is 7) then we consider them to be clinically equivalent. At this level we were unable to show clinical equivalence. In additional, all electrolytes tested showed small but significant bias between the i‐STAT and the central laboratory. Re‐examination of the data excluding all measurements more than 15 minutes apart showed similar findings. Conclusions: At this time we cannot show equivalency between the i‐STAT device and the central laboratory when used under real‐life emergency department conditions. More research is needed is to support or refute these findings.en
dc.typeThesisen
dc.subjectI-Staten
dc.subjectBlood Analyzeren
dc.subjectEmergency Departmenten
dc.subject.meshEmergency Service, Hospitalen
dc.subject.meshLaboratoriesen
dc.descriptionA Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.en
dc.contributor.mentorSarko, John MDen
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