The Regulatory Significance and Molecular Targeting of Novel Non-B-DNA Secondary Structures Formed from the PDGFR-Beta Core Promoter Nuclease Hypersensitivity Element

Persistent Link:
http://hdl.handle.net/10150/337361
Title:
The Regulatory Significance and Molecular Targeting of Novel Non-B-DNA Secondary Structures Formed from the PDGFR-Beta Core Promoter Nuclease Hypersensitivity Element
Author:
Brown, Robert Vincent
Issue Date:
2014
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Embargo:
Release 01-Oct-2015
Abstract:
Herein we describe the regulatory significance and molecular targeting of novel non-B-DNA secondary structures formed from the PDGFR-Beta core promoter nuclease hypersensitivity element.
Type:
text; Electronic Dissertation
Keywords:
i-motif; mechanosensor; molecular switch; PDGFR-β; Transcriptional regulation; Pharmaceutical Sciences; G-quadruplex
Degree Name:
Ph.D.
Degree Level:
doctoral
Degree Program:
Graduate College; Pharmaceutical Sciences
Degree Grantor:
University of Arizona
Advisor:
Hurley, Laurence H.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen
dc.titleThe Regulatory Significance and Molecular Targeting of Novel Non-B-DNA Secondary Structures Formed from the PDGFR-Beta Core Promoter Nuclease Hypersensitivity Elementen_US
dc.creatorBrown, Robert Vincenten_US
dc.contributor.authorBrown, Robert Vincenten_US
dc.date.issued2014-
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.releaseRelease 01-Oct-2015en_US
dc.description.abstractHerein we describe the regulatory significance and molecular targeting of novel non-B-DNA secondary structures formed from the PDGFR-Beta core promoter nuclease hypersensitivity element.en_US
dc.typetexten
dc.typeElectronic Dissertationen
dc.subjecti-motifen_US
dc.subjectmechanosensoren_US
dc.subjectmolecular switchen_US
dc.subjectPDGFR-βen_US
dc.subjectTranscriptional regulationen_US
dc.subjectPharmaceutical Sciencesen_US
dc.subjectG-quadruplexen_US
thesis.degree.namePh.D.en_US
thesis.degree.leveldoctoralen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplinePharmaceutical Sciencesen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorHurley, Laurence H.en_US
dc.contributor.committeememberHurley, Laurence H.en_US
dc.contributor.committeememberSmith, Catharine L.en_US
dc.contributor.committeememberDaekyu, Sunen_US
dc.contributor.committeememberYang, Danzhouen_US
dc.contributor.committeememberWondrak, Georg T.en_US
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