Does Increasing Solids Retention Time During the Wastewater Treatment Process Affect the Persistence of Antibiotic Resistance Genes?

Persistent Link:
http://hdl.handle.net/10150/301697
Title:
Does Increasing Solids Retention Time During the Wastewater Treatment Process Affect the Persistence of Antibiotic Resistance Genes?
Author:
Walston, Stefan Eugene
Issue Date:
2013
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Antibiotic resistance (AR) is reducing options for effective treatment of bacterial infections for clinically ill patients throughout the world. Our investigation examined the impact solids retention time (SRT) may have on the degradation of antibiotic compounds, proliferation of AR bacteria, and the persistence of antibiotic resistance genes (ARGs) during the wastewater treatment process. Results indicate the presence of ARGs related to clinically relevant antibiotics. Data analysis showed that antibiotic classes exhibit different removal efficiencies in the biological treatment processes (i.e. SRT); therefore, operating conditions at each WWTP can be optimized for highest efficiency removal. SRT of 19 days and higher indicated a high removal efficiency for all six ARGs of concern. Ultimately, identifying a critical value to optimize SRTs, where antibiotic degradation is maximized and AR is minimized, will provide information to WWTP operators, allowing treatment optimization to decrease harmful loading of Trace Organic Contaminants (TOrCs) in the environment.
Type:
text; Electronic Thesis
Keywords:
Compounds; Genes; Treatment; Wastewater; Soil, Water & Environmental Science; Antibiotic-Resistance
Degree Name:
M.S.
Degree Level:
masters
Degree Program:
Graduate College; Soil, Water & Environmental Science
Degree Grantor:
University of Arizona
Advisor:
Rock, Channah

Full metadata record

DC FieldValue Language
dc.language.isoenen_US
dc.titleDoes Increasing Solids Retention Time During the Wastewater Treatment Process Affect the Persistence of Antibiotic Resistance Genes?en_US
dc.creatorWalston, Stefan Eugeneen_US
dc.contributor.authorWalston, Stefan Eugeneen_US
dc.date.issued2013-
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractAntibiotic resistance (AR) is reducing options for effective treatment of bacterial infections for clinically ill patients throughout the world. Our investigation examined the impact solids retention time (SRT) may have on the degradation of antibiotic compounds, proliferation of AR bacteria, and the persistence of antibiotic resistance genes (ARGs) during the wastewater treatment process. Results indicate the presence of ARGs related to clinically relevant antibiotics. Data analysis showed that antibiotic classes exhibit different removal efficiencies in the biological treatment processes (i.e. SRT); therefore, operating conditions at each WWTP can be optimized for highest efficiency removal. SRT of 19 days and higher indicated a high removal efficiency for all six ARGs of concern. Ultimately, identifying a critical value to optimize SRTs, where antibiotic degradation is maximized and AR is minimized, will provide information to WWTP operators, allowing treatment optimization to decrease harmful loading of Trace Organic Contaminants (TOrCs) in the environment.en_US
dc.typetexten_US
dc.typeElectronic Thesisen_US
dc.subjectCompoundsen_US
dc.subjectGenesen_US
dc.subjectTreatmenten_US
dc.subjectWastewateren_US
dc.subjectSoil, Water & Environmental Scienceen_US
dc.subjectAntibiotic-Resistanceen_US
thesis.degree.nameM.S.en_US
thesis.degree.levelmastersen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineSoil, Water & Environmental Scienceen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorRock, Channahen_US
dc.contributor.committeememberMcLain, Jeanen_US
dc.contributor.committeememberAbrell, Leifen_US
dc.contributor.committeememberGerrity, Danielen_US
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