1. Mechanistic studies on the formation of glycosyl iodides 2. Synthesis of amino sugars via glycosyl iodides

Persistent Link:
http://hdl.handle.net/10150/291829
Title:
1. Mechanistic studies on the formation of glycosyl iodides 2. Synthesis of amino sugars via glycosyl iodides
Author:
Nguyen, Truc Ngoc, 1972-
Issue Date:
1998
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
The synthesis of oligosaccharides remains a challenging task. In our studies, we applied glycosyl iodides to the synthesis of oligosaccharides. The mechanism of formation of glycosyl iodides from anomeric acetates of glucose, galactose and mannose, and 1,2 and 1,6 anhydro sugars were investigated by NMR. Glycosyl iodides were then applied in glycosidation studies and specifically in the synthesis of a precursor to the trisaccharide of Lewis x, a blood group antigen.
Type:
text; Thesis-Reproduction (electronic)
Keywords:
Chemistry, Organic.
Degree Name:
M.S.
Degree Level:
masters
Degree Program:
Graduate College; Chemistry
Degree Grantor:
University of Arizona
Advisor:
Gervay, Jacquelyn

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_US
dc.title1. Mechanistic studies on the formation of glycosyl iodides 2. Synthesis of amino sugars via glycosyl iodidesen_US
dc.creatorNguyen, Truc Ngoc, 1972-en_US
dc.contributor.authorNguyen, Truc Ngoc, 1972-en_US
dc.date.issued1998en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractThe synthesis of oligosaccharides remains a challenging task. In our studies, we applied glycosyl iodides to the synthesis of oligosaccharides. The mechanism of formation of glycosyl iodides from anomeric acetates of glucose, galactose and mannose, and 1,2 and 1,6 anhydro sugars were investigated by NMR. Glycosyl iodides were then applied in glycosidation studies and specifically in the synthesis of a precursor to the trisaccharide of Lewis x, a blood group antigen.en_US
dc.typetexten_US
dc.typeThesis-Reproduction (electronic)en_US
dc.subjectChemistry, Organic.en_US
thesis.degree.nameM.S.en_US
thesis.degree.levelmastersen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineChemistryen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorGervay, Jacquelynen_US
dc.identifier.proquest1389292en_US
dc.identifier.bibrecord.b38553958en_US
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