Occupational exposure to azinphos-methyl: Correlating biological markers to environmental residue levels

Persistent Link:
http://hdl.handle.net/10150/291604
Title:
Occupational exposure to azinphos-methyl: Correlating biological markers to environmental residue levels
Author:
Gonzales, Melissa, 1963-
Issue Date:
1992
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Peach harvester exposure to azinphos-methyl (AZM) residues estimated by the Transfer Factor (TF) ratio of Dislodgeable Foliar Residue (DFR) to Daily Dermal Exposure (DDE) was compared to estimates based on the relationship between dermal exposure and dialkylphosphate metabolite excretion. DFR was monitored in four orchards from the time of pesticide application through harvest. Eleven male harvesters wore cotton tee-shirt dosimeters and provided area-specific skin washes and wipes for DDE monitoring during work operations. Urinary dialkylphosphate metabolites of AZM were also monitored and compared to DDE results. During a later harvest for which DDE was not determined, the dermal exposure estimated by the TF (1,310 μg) was comparable to the estimates based on dialkylphosphate excretion (1,456-1,534 μg). A repeated measures ANOVA showed that harvesters' cholinesterase levels were significantly lower than 'non-harvesters'. No significant reductions in cholinesterase levels were detected over time.
Type:
text; Thesis-Reproduction (electronic)
Keywords:
Health Sciences, Occupational Health and Safety.; Health Sciences, Toxicology.; Environmental Sciences.
Degree Name:
M.S.
Degree Level:
masters
Degree Program:
Graduate College; Pharmacology and Toxicology
Degree Grantor:
University of Arizona
Advisor:
Crutchfield, Clifton D.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_US
dc.titleOccupational exposure to azinphos-methyl: Correlating biological markers to environmental residue levelsen_US
dc.creatorGonzales, Melissa, 1963-en_US
dc.contributor.authorGonzales, Melissa, 1963-en_US
dc.date.issued1992en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractPeach harvester exposure to azinphos-methyl (AZM) residues estimated by the Transfer Factor (TF) ratio of Dislodgeable Foliar Residue (DFR) to Daily Dermal Exposure (DDE) was compared to estimates based on the relationship between dermal exposure and dialkylphosphate metabolite excretion. DFR was monitored in four orchards from the time of pesticide application through harvest. Eleven male harvesters wore cotton tee-shirt dosimeters and provided area-specific skin washes and wipes for DDE monitoring during work operations. Urinary dialkylphosphate metabolites of AZM were also monitored and compared to DDE results. During a later harvest for which DDE was not determined, the dermal exposure estimated by the TF (1,310 μg) was comparable to the estimates based on dialkylphosphate excretion (1,456-1,534 μg). A repeated measures ANOVA showed that harvesters' cholinesterase levels were significantly lower than 'non-harvesters'. No significant reductions in cholinesterase levels were detected over time.en_US
dc.typetexten_US
dc.typeThesis-Reproduction (electronic)en_US
dc.subjectHealth Sciences, Occupational Health and Safety.en_US
dc.subjectHealth Sciences, Toxicology.en_US
dc.subjectEnvironmental Sciences.en_US
thesis.degree.nameM.S.en_US
thesis.degree.levelmastersen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplinePharmacology and Toxicologyen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorCrutchfield, Clifton D.en_US
dc.identifier.proquest1347575en_US
dc.identifier.bibrecord.b27474653en_US
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