Synthesis and characterization of oxomolybdenum(V) compounds with two or three thiolate donor atoms: Analogues for the molybdenum center of sulfite oxidase

Persistent Link:
http://hdl.handle.net/10150/284099
Title:
Synthesis and characterization of oxomolybdenum(V) compounds with two or three thiolate donor atoms: Analogues for the molybdenum center of sulfite oxidase
Author:
Mader, Michele Lynn
Issue Date:
2000
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
The MoOS₃ active site of sulfite oxidase has drawn attention to a relatively unexplored area of molybdenum coordination chemistry. Cis,trans-(L-N₂S₂)MoᵛO(SR)[L-N₂S₂H₂ = N,N '-dimethyl-N,N'-bis(mercaptophenyl)ethylenediamine: R = CH₂Ph. CH₂CH₃, and p-C₆H₄-Y (Y = CF₃, Cl, Br, F, H, CH₃, CH₂CH₃, and OCH₃)] are the first structurally, spectroscopically, and electrochemically characterized mononuclear Mo compounds with three thiolate donors in the equatorial, as occurs in sulfite oxidase. These compounds provide a well-defined platform for the systematic investigation of the electronic structures of the MoᵛOS₃ centers and their implications for molybdoenzymes. Single crystal electron paramagnetic resonance spectroscopy was used to study cis,trans-(L-N₂S₂)MoᵛOCl and determine the relationship between the molecular and magnetic structure. These studies furnish a better understanding of the CW-EPR parameters exhibited by the various Mo(V) forms of the mononuclear molybdenum enzymes.
Type:
text; Dissertation-Reproduction (electronic)
Keywords:
Chemistry, Inorganic.
Degree Name:
Ph.D.
Degree Level:
doctoral
Degree Program:
Graduate College; Chemistry
Degree Grantor:
University of Arizona
Advisor:
Enemark, John H.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_US
dc.titleSynthesis and characterization of oxomolybdenum(V) compounds with two or three thiolate donor atoms: Analogues for the molybdenum center of sulfite oxidaseen_US
dc.creatorMader, Michele Lynnen_US
dc.contributor.authorMader, Michele Lynnen_US
dc.date.issued2000en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractThe MoOS₃ active site of sulfite oxidase has drawn attention to a relatively unexplored area of molybdenum coordination chemistry. Cis,trans-(L-N₂S₂)MoᵛO(SR)[L-N₂S₂H₂ = N,N '-dimethyl-N,N'-bis(mercaptophenyl)ethylenediamine: R = CH₂Ph. CH₂CH₃, and p-C₆H₄-Y (Y = CF₃, Cl, Br, F, H, CH₃, CH₂CH₃, and OCH₃)] are the first structurally, spectroscopically, and electrochemically characterized mononuclear Mo compounds with three thiolate donors in the equatorial, as occurs in sulfite oxidase. These compounds provide a well-defined platform for the systematic investigation of the electronic structures of the MoᵛOS₃ centers and their implications for molybdoenzymes. Single crystal electron paramagnetic resonance spectroscopy was used to study cis,trans-(L-N₂S₂)MoᵛOCl and determine the relationship between the molecular and magnetic structure. These studies furnish a better understanding of the CW-EPR parameters exhibited by the various Mo(V) forms of the mononuclear molybdenum enzymes.en_US
dc.typetexten_US
dc.typeDissertation-Reproduction (electronic)en_US
dc.subjectChemistry, Inorganic.en_US
thesis.degree.namePh.D.en_US
thesis.degree.leveldoctoralen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineChemistryen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorEnemark, John H.en_US
dc.identifier.proquest9965880en_US
dc.identifier.bibrecord.b40480550en_US
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