INTERSPECIES TRANSFER OF DELAYED HYPERSENSITIVITY WITH TRANSFER FACTOR

Persistent Link:
http://hdl.handle.net/10150/282271
Title:
INTERSPECIES TRANSFER OF DELAYED HYPERSENSITIVITY WITH TRANSFER FACTOR
Author:
Soli, Teri Cullen
Issue Date:
1980
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Dialyzable leucocytic extracts (Transfer Factor) were prepared from guinea pigs, rabbits, dogs and cattle sensitized to tuberculin, from cattle and dogs reactive to coccidioidin and from cattle sensitized to 2,4 dinitrochlorobenzene and Pasteurella multocida. These Transfer Factor (TF) preparations were used in intra- and interspecies transfers of delayed hypersensitivity (DH) and cellular immunity (CMI) in guinea pigs, rabbits, dogs, cattle and humans. Various doses and routes of administration were employed. Success of transfer was based upon dermal skin reactivity and/or clinical improvement. Our results suggest the following: (a) interspecies transfer of DH is effective with a variety of species, (b) oral administration of TF is effective and (c) cattle are effective donors of TF for use in humans and other animals because of potential quantity and strong potency of transfer material.
Type:
text; Dissertation-Reproduction (electronic)
Keywords:
Delayed hypersensitivity.; Transfer factor (Immunology); Immunospecificity.
Degree Name:
Ph.D.
Degree Level:
doctoral
Degree Program:
Graduate College; Microbiology and Medical Technology
Degree Grantor:
University of Arizona
Advisor:
Jeter, Wayburn S.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_US
dc.titleINTERSPECIES TRANSFER OF DELAYED HYPERSENSITIVITY WITH TRANSFER FACTORen_US
dc.creatorSoli, Teri Cullenen_US
dc.contributor.authorSoli, Teri Cullenen_US
dc.date.issued1980en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractDialyzable leucocytic extracts (Transfer Factor) were prepared from guinea pigs, rabbits, dogs and cattle sensitized to tuberculin, from cattle and dogs reactive to coccidioidin and from cattle sensitized to 2,4 dinitrochlorobenzene and Pasteurella multocida. These Transfer Factor (TF) preparations were used in intra- and interspecies transfers of delayed hypersensitivity (DH) and cellular immunity (CMI) in guinea pigs, rabbits, dogs, cattle and humans. Various doses and routes of administration were employed. Success of transfer was based upon dermal skin reactivity and/or clinical improvement. Our results suggest the following: (a) interspecies transfer of DH is effective with a variety of species, (b) oral administration of TF is effective and (c) cattle are effective donors of TF for use in humans and other animals because of potential quantity and strong potency of transfer material.en_US
dc.typetexten_US
dc.typeDissertation-Reproduction (electronic)en_US
dc.subjectDelayed hypersensitivity.en_US
dc.subjectTransfer factor (Immunology)en_US
dc.subjectImmunospecificity.en_US
thesis.degree.namePh.D.en_US
thesis.degree.leveldoctoralen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineMicrobiology and Medical Technologyen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorJeter, Wayburn S.en_US
dc.identifier.proquest8017808en_US
dc.identifier.oclc8633089en_US
dc.identifier.bibrecord.b13886113en_US
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