Multiple maps and multiple reference frames in the hippocampal representation of space

Persistent Link:
http://hdl.handle.net/10150/282164
Title:
Multiple maps and multiple reference frames in the hippocampal representation of space
Author:
Gothard, Katalin Margit, 1960-
Issue Date:
1996
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Populations of simultaneously recorded hippocampal place cells were studied in three tasks that required shuttling between a variably placed box and a reward location predicted by fixed or variably located landmarks. Groups of place cells fired at fixed locations relative to the behaviorally relevant landmarks or to the absolute spatial framework of the environment. The initial segment of the journeys was represented by a sequence of cells that fired at fixed distances with respect to the landmark of origin, behind the animal, irrespective of where that landmark was located. The final segments of the journeys were represented by cells that fired at fixed locations relative to the landmark of destination. We propose that on the initial parts of the journey, the spatial coordinate represented by each cell was updated predominantly by path integration. When approaching the landmark of destination, the coordinates were updated and corrected by visual landmarks (or other sensory cues). The intermediate zone was characterized by a transition from the reference frame of the origin to the reference frame of the destination. Small distortion of the environment led to a smooth, continuous transition, while a large distortion led to abrupt transitions. These observations suggest that in the hippocampus, place can be represented in multiple spatial reference frames established by behaviorally relevant landmarks. Further experiments showed that these landmarks, or their sensory properties, are not represented explicitly by place cells, because cells did not maintain their landmark-related firing in a similar task, performed in a different environment.
Type:
text; Dissertation-Reproduction (electronic)
Keywords:
Biology, Neuroscience.; Biology, Animal Physiology.; Psychology, Cognitive.
Degree Name:
Ph.D.
Degree Level:
doctoral
Degree Program:
Graduate College; Neurosciences
Degree Grantor:
University of Arizona
Advisor:
McNaughton, Bruce L.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_US
dc.titleMultiple maps and multiple reference frames in the hippocampal representation of spaceen_US
dc.creatorGothard, Katalin Margit, 1960-en_US
dc.contributor.authorGothard, Katalin Margit, 1960-en_US
dc.date.issued1996en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractPopulations of simultaneously recorded hippocampal place cells were studied in three tasks that required shuttling between a variably placed box and a reward location predicted by fixed or variably located landmarks. Groups of place cells fired at fixed locations relative to the behaviorally relevant landmarks or to the absolute spatial framework of the environment. The initial segment of the journeys was represented by a sequence of cells that fired at fixed distances with respect to the landmark of origin, behind the animal, irrespective of where that landmark was located. The final segments of the journeys were represented by cells that fired at fixed locations relative to the landmark of destination. We propose that on the initial parts of the journey, the spatial coordinate represented by each cell was updated predominantly by path integration. When approaching the landmark of destination, the coordinates were updated and corrected by visual landmarks (or other sensory cues). The intermediate zone was characterized by a transition from the reference frame of the origin to the reference frame of the destination. Small distortion of the environment led to a smooth, continuous transition, while a large distortion led to abrupt transitions. These observations suggest that in the hippocampus, place can be represented in multiple spatial reference frames established by behaviorally relevant landmarks. Further experiments showed that these landmarks, or their sensory properties, are not represented explicitly by place cells, because cells did not maintain their landmark-related firing in a similar task, performed in a different environment.en_US
dc.typetexten_US
dc.typeDissertation-Reproduction (electronic)en_US
dc.subjectBiology, Neuroscience.en_US
dc.subjectBiology, Animal Physiology.en_US
dc.subjectPsychology, Cognitive.en_US
thesis.degree.namePh.D.en_US
thesis.degree.leveldoctoralen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineNeurosciencesen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorMcNaughton, Bruce L.en_US
dc.identifier.proquest9713397en_US
dc.identifier.bibrecord.b34396123en_US
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