Additional indications for genetic counseling in women of advanced maternal age

Persistent Link:
http://hdl.handle.net/10150/276901
Title:
Additional indications for genetic counseling in women of advanced maternal age
Author:
Hays, Francis Myron, 1963-
Issue Date:
1988
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Genetic counseling for women with advanced maternal age is well established medical standard of care. However, only one study has yet been done to test the validity of that policy. Records of 283 patients referred for genetic counseling with advanced maternal age as a primary indication were examined. Of these, 57.6% had at least one additional indication. This value did differ significantly from Rubin's data which reported a 43.3% rate (X2 = 13.01, p > 0.001). The additional indications were broken down according to McKusick's system, and a statistical difference between my and Rubin's data was found in the autosomal dominant, autosomal recessive, potential teratogenic exposure and miscellaneous categories. There was no significant statistical difference between my and Rubin's data in the X-linked, chromosomal anomalies and multifactorial groups. These data underscore the need for physicians to refer patients with advanced maternal age for genetic counseling, and provides a scientific basis for doing so.
Type:
text; Thesis-Reproduction (electronic)
Keywords:
Genetic counseling.; Maternal age.; Pregnancy in middle age.
Degree Name:
M.S.
Degree Level:
masters
Degree Program:
Graduate College; Genetics
Degree Grantor:
University of Arizona
Advisor:
Hoyme, H. Eugene

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_US
dc.titleAdditional indications for genetic counseling in women of advanced maternal ageen_US
dc.creatorHays, Francis Myron, 1963-en_US
dc.contributor.authorHays, Francis Myron, 1963-en_US
dc.date.issued1988en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractGenetic counseling for women with advanced maternal age is well established medical standard of care. However, only one study has yet been done to test the validity of that policy. Records of 283 patients referred for genetic counseling with advanced maternal age as a primary indication were examined. Of these, 57.6% had at least one additional indication. This value did differ significantly from Rubin's data which reported a 43.3% rate (X2 = 13.01, p > 0.001). The additional indications were broken down according to McKusick's system, and a statistical difference between my and Rubin's data was found in the autosomal dominant, autosomal recessive, potential teratogenic exposure and miscellaneous categories. There was no significant statistical difference between my and Rubin's data in the X-linked, chromosomal anomalies and multifactorial groups. These data underscore the need for physicians to refer patients with advanced maternal age for genetic counseling, and provides a scientific basis for doing so.en_US
dc.typetexten_US
dc.typeThesis-Reproduction (electronic)en_US
dc.subjectGenetic counseling.en_US
dc.subjectMaternal age.en_US
dc.subjectPregnancy in middle age.en_US
thesis.degree.nameM.S.en_US
thesis.degree.levelmastersen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineGeneticsen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorHoyme, H. Eugeneen_US
dc.identifier.proquest1335823en_US
dc.identifier.oclc22350727en_US
dc.identifier.bibrecord.b17413230en_US
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