A non-invasive method of estimating pulmonary artery pressure in the total artificial heart

Persistent Link:
http://hdl.handle.net/10150/276785
Title:
A non-invasive method of estimating pulmonary artery pressure in the total artificial heart
Author:
Vonesh, Michael John, 1964-
Issue Date:
1988
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
A non-invasive, in vitro method of estimating mean pulmonary artery pressure (PAP) was developed. This information was obtained by establishing a relationship between the pneumatic right drive pressure (RDP) and PAP waveforms. The RDP-PAP relationship was formalized into a series of multiple-linear regression equations for TAH cardiac cycles of known fill volume (FV). Correlation of computed estimates of PAP to actual measurements showed that these equations were greater than 92% accurate within 1.84 mmHg. In addition, while the RDP-PAP relationships were wholly dependent on FV, it was shown that they are independent of the manner in which FV was obtained. This method proved useful over the clinical operating range of the pneumatic heart driver, as well as over the normal physiological range of PAP in the human. Effectiveness of this method in vivo needs to be demonstrated.
Type:
text; Thesis-Reproduction (electronic)
Keywords:
Heart, Artificial.; Diagnosis, Noninvasive.; Blood pressure -- Measurement.
Degree Name:
M.S.
Degree Level:
masters
Degree Program:
Graduate College; Electrical and Computer Engineering
Degree Grantor:
University of Arizona
Advisor:
Mylrea, Kenneth C.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_US
dc.titleA non-invasive method of estimating pulmonary artery pressure in the total artificial hearten_US
dc.creatorVonesh, Michael John, 1964-en_US
dc.contributor.authorVonesh, Michael John, 1964-en_US
dc.date.issued1988en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractA non-invasive, in vitro method of estimating mean pulmonary artery pressure (PAP) was developed. This information was obtained by establishing a relationship between the pneumatic right drive pressure (RDP) and PAP waveforms. The RDP-PAP relationship was formalized into a series of multiple-linear regression equations for TAH cardiac cycles of known fill volume (FV). Correlation of computed estimates of PAP to actual measurements showed that these equations were greater than 92% accurate within 1.84 mmHg. In addition, while the RDP-PAP relationships were wholly dependent on FV, it was shown that they are independent of the manner in which FV was obtained. This method proved useful over the clinical operating range of the pneumatic heart driver, as well as over the normal physiological range of PAP in the human. Effectiveness of this method in vivo needs to be demonstrated.en_US
dc.typetexten_US
dc.typeThesis-Reproduction (electronic)en_US
dc.subjectHeart, Artificial.en_US
dc.subjectDiagnosis, Noninvasive.en_US
dc.subjectBlood pressure -- Measurement.en_US
thesis.degree.nameM.S.en_US
thesis.degree.levelmastersen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineElectrical and Computer Engineeringen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorMylrea, Kenneth C.en_US
dc.identifier.proquest1334313en_US
dc.identifier.oclc21389297en_US
dc.identifier.bibrecord.b17236320en_US
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