Persistent Link:
http://hdl.handle.net/10150/276633
Title:
The effect of trenbolone on skeletal muscle satellite cells
Author:
Thompson, Steven Howard, 1958-
Issue Date:
1987
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Young female rats treated with trenbolone demonstrated an increase in weight gain per day and overall weight increase during the treatment period. Trenbolone treated rats also experienced improved feed efficiency. Muscles removed from the lower hind limb of trenbolone treated rats had a greater DNA to protein ratio than muscles from control animals. However, there was no significant difference in wet muscle weight between trenbolone treated and control muscles. Satellite cells from untreated female rats were not responsive to trenbolone added in vitro. In studies utilizing serum free medium, trenbolone alone, and in the presence of growth factors, could not stimulate proliferation above controls. In similar serum free medium studies, satellite cells from trenbolone treated rats were more responsive to growth factors than cells from control rats.
Type:
text; Thesis-Reproduction (electronic)
Keywords:
Anabolic steroids.; Muscles -- Growth.; Growth factors.; Satellite cells.
Degree Name:
M.S.
Degree Level:
masters
Degree Program:
Graduate College; Animal Sciences
Degree Grantor:
University of Arizona
Advisor:
Allen, Ronald E.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_US
dc.titleThe effect of trenbolone on skeletal muscle satellite cellsen_US
dc.creatorThompson, Steven Howard, 1958-en_US
dc.contributor.authorThompson, Steven Howard, 1958-en_US
dc.date.issued1987en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractYoung female rats treated with trenbolone demonstrated an increase in weight gain per day and overall weight increase during the treatment period. Trenbolone treated rats also experienced improved feed efficiency. Muscles removed from the lower hind limb of trenbolone treated rats had a greater DNA to protein ratio than muscles from control animals. However, there was no significant difference in wet muscle weight between trenbolone treated and control muscles. Satellite cells from untreated female rats were not responsive to trenbolone added in vitro. In studies utilizing serum free medium, trenbolone alone, and in the presence of growth factors, could not stimulate proliferation above controls. In similar serum free medium studies, satellite cells from trenbolone treated rats were more responsive to growth factors than cells from control rats.en_US
dc.typetexten_US
dc.typeThesis-Reproduction (electronic)en_US
dc.subjectAnabolic steroids.en_US
dc.subjectMuscles -- Growth.en_US
dc.subjectGrowth factors.en_US
dc.subjectSatellite cells.en_US
thesis.degree.nameM.S.en_US
thesis.degree.levelmastersen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineAnimal Sciencesen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorAllen, Ronald E.en_US
dc.identifier.proquest1332546en_US
dc.identifier.oclc20061338en_US
dc.identifier.bibrecord.b16916566en_US
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