Persistent Link:
http://hdl.handle.net/10150/202701
Title:
Speciation and Reduced Hybrid Female Fertility in House Mice
Author:
Suzuki, Taichi A.
Issue Date:
2011
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
I asked whether there is female sterility in hybrid offspring of Mus musculus domesticus and M. m. musculus using two wild derived inbred strains representing each subspecies. I evaluated F1 hybrid female fertility by crossing F1 females to a tester male and comparing multiple reproductive parameters between intra-subspecific controls and inter-subspecific hybrids. Hybrid females had smaller litter size, reduced embryo survival, fewer ovulations, and fewer small follicles relative to controls. Significant variation in reproductive parameters was seen among different genotypes. Genes contributing to hybrid female infertility are polymorphic within subspecies. Differences in reproductive phenotypes in F1's of reciprocal crosses suggest that female subfertility may be due to either cyto-nuclear incompatibility or to imprinting. These findings suggest a greater complexity in hybrid sterility than has been previously appreciated and highlight the potential importance of hybrid female sterility in the early stages of speciation.
Type:
text; Electronic Thesis
Keywords:
House mice; Hybrid; Reproduction; Speciation; Ecology & Evolutionary Biology; Female; Fertility
Degree Name:
M.S.
Degree Level:
masters
Degree Program:
Graduate College; Ecology & Evolutionary Biology
Degree Grantor:
University of Arizona
Advisor:
Nachman, Michael W.

Full metadata record

DC FieldValue Language
dc.language.isoenen_US
dc.titleSpeciation and Reduced Hybrid Female Fertility in House Miceen_US
dc.creatorSuzuki, Taichi A.en_US
dc.contributor.authorSuzuki, Taichi A.en_US
dc.date.issued2011-
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractI asked whether there is female sterility in hybrid offspring of Mus musculus domesticus and M. m. musculus using two wild derived inbred strains representing each subspecies. I evaluated F1 hybrid female fertility by crossing F1 females to a tester male and comparing multiple reproductive parameters between intra-subspecific controls and inter-subspecific hybrids. Hybrid females had smaller litter size, reduced embryo survival, fewer ovulations, and fewer small follicles relative to controls. Significant variation in reproductive parameters was seen among different genotypes. Genes contributing to hybrid female infertility are polymorphic within subspecies. Differences in reproductive phenotypes in F1's of reciprocal crosses suggest that female subfertility may be due to either cyto-nuclear incompatibility or to imprinting. These findings suggest a greater complexity in hybrid sterility than has been previously appreciated and highlight the potential importance of hybrid female sterility in the early stages of speciation.en_US
dc.typetexten_US
dc.typeElectronic Thesisen_US
dc.subjectHouse miceen_US
dc.subjectHybriden_US
dc.subjectReproductionen_US
dc.subjectSpeciationen_US
dc.subjectEcology & Evolutionary Biologyen_US
dc.subjectFemaleen_US
dc.subjectFertilityen_US
thesis.degree.nameM.S.en_US
thesis.degree.levelmastersen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineEcology & Evolutionary Biologyen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorNachman, Michael W.en_US
dc.contributor.committeememberHammer, Michael F.en_US
dc.contributor.committeememberWhiteman, Noahen_US
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