The Effect of Frontal Lobe Function on Proverb Interpretation in Parkinson's Disease

Persistent Link:
http://hdl.handle.net/10150/195947
Title:
The Effect of Frontal Lobe Function on Proverb Interpretation in Parkinson's Disease
Author:
Gutmann, Michelle
Issue Date:
2009
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
The cognitive impairment associated with PD involves a broad range of deficits including difficulty with executive functions such as working memory, inhibition, decision-making, and cognitive multitasking, learning, and visuoperceptual skills. Even early in the disease, when motor symptoms tend to predominate, there is evidence that cognitive functions can be compromised. Owing to the presence of executive-type dysfunction in PD, some researchers likened the cognitive deficit of PD to that seen with frontal lobe damage. The anatomical basis of PD, however, suggests otherwise. Dopamine depletion in the basal ganglia, and the downstream depletion of dopamine in the frontostriatal circuitry is often thought to be the foundation of the cognitive deficits associated with PD.In addition to cognitive impairments, a language deficit attends Parkinson's disease (PD) alongside the other motor and non-motor aspects of the disease. This language deficit is characterized by difficulty processing various types of figurative language, and has been associated with various PD-related cognitive deficits, such as deficits in working memory (WM). Varied assessment tools have been used to characterize the neuropsychological functions associated with this language deficit, most of which involve some measure of frontally-based cognitive skills.The purpose of this study was to examine the influence of frontal lobe function on higher-level language function in the non-demented PD (NDPD) population. To investigate this influence, the performance of two groups of participants (i.e., one NDPD group and one control group) was compared on both a proverb interpretation task and on a statistically derived measure of frontal lobe function.Results indicated a relation between performance on the measure of frontal lobe function and performance on the proverb interpretation task in the PD group only. Significant findings are discussed in relation to the neuropsychological underpinnings of the figurative language deficit in PD.
Type:
text; Electronic Dissertation
Keywords:
cognition; language; Parkinson's disease; proverbs
Degree Name:
Ph.D.
Degree Level:
doctoral
Degree Program:
Speech, Language, & Hearing Sciences; Graduate College
Degree Grantor:
University of Arizona
Committee Chair:
Story, Brad H.

Full metadata record

DC FieldValue Language
dc.language.isoENen_US
dc.titleThe Effect of Frontal Lobe Function on Proverb Interpretation in Parkinson's Diseaseen_US
dc.creatorGutmann, Michelleen_US
dc.contributor.authorGutmann, Michelleen_US
dc.date.issued2009en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractThe cognitive impairment associated with PD involves a broad range of deficits including difficulty with executive functions such as working memory, inhibition, decision-making, and cognitive multitasking, learning, and visuoperceptual skills. Even early in the disease, when motor symptoms tend to predominate, there is evidence that cognitive functions can be compromised. Owing to the presence of executive-type dysfunction in PD, some researchers likened the cognitive deficit of PD to that seen with frontal lobe damage. The anatomical basis of PD, however, suggests otherwise. Dopamine depletion in the basal ganglia, and the downstream depletion of dopamine in the frontostriatal circuitry is often thought to be the foundation of the cognitive deficits associated with PD.In addition to cognitive impairments, a language deficit attends Parkinson's disease (PD) alongside the other motor and non-motor aspects of the disease. This language deficit is characterized by difficulty processing various types of figurative language, and has been associated with various PD-related cognitive deficits, such as deficits in working memory (WM). Varied assessment tools have been used to characterize the neuropsychological functions associated with this language deficit, most of which involve some measure of frontally-based cognitive skills.The purpose of this study was to examine the influence of frontal lobe function on higher-level language function in the non-demented PD (NDPD) population. To investigate this influence, the performance of two groups of participants (i.e., one NDPD group and one control group) was compared on both a proverb interpretation task and on a statistically derived measure of frontal lobe function.Results indicated a relation between performance on the measure of frontal lobe function and performance on the proverb interpretation task in the PD group only. Significant findings are discussed in relation to the neuropsychological underpinnings of the figurative language deficit in PD.en_US
dc.typetexten_US
dc.typeElectronic Dissertationen_US
dc.subjectcognitionen_US
dc.subjectlanguageen_US
dc.subjectParkinson's diseaseen_US
dc.subjectproverbsen_US
thesis.degree.namePh.D.en_US
thesis.degree.leveldoctoralen_US
thesis.degree.disciplineSpeech, Language, & Hearing Sciencesen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.chairStory, Brad H.en_US
dc.contributor.committeememberStory, Brad H.en_US
dc.contributor.committeememberSherman, Scotten_US
dc.contributor.committeememberGlisky, Elizabethen_US
dc.contributor.committeememberHolland, Audreyen_US
dc.contributor.committeememberBunton, Kateen_US
dc.identifier.proquest10347en_US
dc.identifier.oclc659752117en_US
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