Examining the Relationship between Behavioral Repetition Priming and fMRI Repetition Suppression

Persistent Link:
http://hdl.handle.net/10150/193841
Title:
Examining the Relationship between Behavioral Repetition Priming and fMRI Repetition Suppression
Author:
Lin, Chun-Yu
Issue Date:
2009
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Priming refers to a change in the ability to identify, produce, or classify a stimulus as a result of a previous encounter with the same or a related stimulus. Recent neuroimaging studies often found behavioral priming to co-occur with a reduction in neural activations in various cortical regions, which is called repetition suppression. It is thought that repetition suppression is closely related to behavioral priming, and may even be the underlying neural mechanism that supports priming. However, current literature still has several unsolved questions about the relationship between repetition suppression and priming. The present dissertation set out to further elucidate their relationship. In Study 1, a mirror-word identification task was used to limit overlap between study and test to a primarily perceptual level with little or no conceptual overlap nor top-down modulation. Repetition suppression was found in visual perceptual and frontal phonological regions involved at both study and test, supporting a "component process" view that repetition suppression and priming can occur at a perceptual level with limited conceptual or top-down processes involved. In Study 2, three perceptual priming tasks and one conceptual priming task were used to directly examine component process view's prediction that perceptual priming would be correlated with posterior repetition suppression and conceptual priming would be correlated with frontal repetition suppression. The results showed that both perceptual and conceptual priming involved repetition suppression in both frontal and posterior perceptual regions, at least when measured with our paradigm and tasks, and both frontal and posterior repetition suppression effects were correlated with behavioral priming in all four perceptual and conceptual priming tasks. This finding suggests that both frontal and posterior perceptual regions are involved in perceptual and conceptual priming, and that they are most likely working in concert with one another during priming, as exemplified by an interactive view of priming. Taken together, our data suggest that priming may be supported by several different underlying mechanisms, such as bottom-up processes (component process view of priming), top-down modulation and frontal-posterior interaction/synchrony.
Type:
text; Electronic Dissertation
Keywords:
fMRI; memory; priming; repetition suppression
Degree Name:
Ph.D.
Degree Level:
doctoral
Degree Program:
Psychology; Graduate College
Degree Grantor:
University of Arizona
Advisor:
Ryan, Lee
Committee Chair:
Ryan, Lee

Full metadata record

DC FieldValue Language
dc.language.isoENen_US
dc.titleExamining the Relationship between Behavioral Repetition Priming and fMRI Repetition Suppressionen_US
dc.creatorLin, Chun-Yuen_US
dc.contributor.authorLin, Chun-Yuen_US
dc.date.issued2009en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractPriming refers to a change in the ability to identify, produce, or classify a stimulus as a result of a previous encounter with the same or a related stimulus. Recent neuroimaging studies often found behavioral priming to co-occur with a reduction in neural activations in various cortical regions, which is called repetition suppression. It is thought that repetition suppression is closely related to behavioral priming, and may even be the underlying neural mechanism that supports priming. However, current literature still has several unsolved questions about the relationship between repetition suppression and priming. The present dissertation set out to further elucidate their relationship. In Study 1, a mirror-word identification task was used to limit overlap between study and test to a primarily perceptual level with little or no conceptual overlap nor top-down modulation. Repetition suppression was found in visual perceptual and frontal phonological regions involved at both study and test, supporting a "component process" view that repetition suppression and priming can occur at a perceptual level with limited conceptual or top-down processes involved. In Study 2, three perceptual priming tasks and one conceptual priming task were used to directly examine component process view's prediction that perceptual priming would be correlated with posterior repetition suppression and conceptual priming would be correlated with frontal repetition suppression. The results showed that both perceptual and conceptual priming involved repetition suppression in both frontal and posterior perceptual regions, at least when measured with our paradigm and tasks, and both frontal and posterior repetition suppression effects were correlated with behavioral priming in all four perceptual and conceptual priming tasks. This finding suggests that both frontal and posterior perceptual regions are involved in perceptual and conceptual priming, and that they are most likely working in concert with one another during priming, as exemplified by an interactive view of priming. Taken together, our data suggest that priming may be supported by several different underlying mechanisms, such as bottom-up processes (component process view of priming), top-down modulation and frontal-posterior interaction/synchrony.en_US
dc.typetexten_US
dc.typeElectronic Dissertationen_US
dc.subjectfMRIen_US
dc.subjectmemoryen_US
dc.subjectprimingen_US
dc.subjectrepetition suppressionen_US
thesis.degree.namePh.D.en_US
thesis.degree.leveldoctoralen_US
thesis.degree.disciplinePsychologyen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorRyan, Leeen_US
dc.contributor.chairRyan, Leeen_US
dc.contributor.committeememberNadel, Lynnen_US
dc.contributor.committeememberGlisky, Elizabethen_US
dc.contributor.committeememberForster, Kennethen_US
dc.identifier.proquest10776en_US
dc.identifier.oclc659753619en_US
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