Effects of Conjugated Linoleic Acid on Body Composition Parameters in Aged and Cachectic Mice

Persistent Link:
http://hdl.handle.net/10150/193366
Title:
Effects of Conjugated Linoleic Acid on Body Composition Parameters in Aged and Cachectic Mice
Author:
Carroll, Shannon
Issue Date:
2007
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Research for this thesis consisted of three parts; determining CLA effects on 1) whole animal body composition in aged mice, 2) whole animal body composition parameters in a murine model of cachexia, 3) specific muscles, adipose depots, and organs as well as the effects on parameters of muscle degradation in aged mice. The first study indicates CLA decreased fat mass and increased whole animal protein mass in aged mice. In the second study, infection resulted in changes in carcass water, fat, and protein. CLA caused an increase in protein mass in the controls but was unable to increase protein mass in cachectic animals. In the third study, no changes in muscle weights were observed with CLA and there was no effect on parameters of muscle degradation. These results demonstrate the complex nature of CLA and the need for further investigation.
Type:
text; Electronic Thesis
Degree Name:
MS
Degree Level:
masters
Degree Program:
Animal Sciences; Graduate College
Degree Grantor:
University of Arizona
Committee Chair:
Baumgard, Lance H.

Full metadata record

DC FieldValue Language
dc.language.isoENen_US
dc.titleEffects of Conjugated Linoleic Acid on Body Composition Parameters in Aged and Cachectic Miceen_US
dc.creatorCarroll, Shannonen_US
dc.contributor.authorCarroll, Shannonen_US
dc.date.issued2007en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractResearch for this thesis consisted of three parts; determining CLA effects on 1) whole animal body composition in aged mice, 2) whole animal body composition parameters in a murine model of cachexia, 3) specific muscles, adipose depots, and organs as well as the effects on parameters of muscle degradation in aged mice. The first study indicates CLA decreased fat mass and increased whole animal protein mass in aged mice. In the second study, infection resulted in changes in carcass water, fat, and protein. CLA caused an increase in protein mass in the controls but was unable to increase protein mass in cachectic animals. In the third study, no changes in muscle weights were observed with CLA and there was no effect on parameters of muscle degradation. These results demonstrate the complex nature of CLA and the need for further investigation.en_US
dc.typetexten_US
dc.typeElectronic Thesisen_US
thesis.degree.nameMSen_US
thesis.degree.levelmastersen_US
thesis.degree.disciplineAnimal Sciencesen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.chairBaumgard, Lance H.en_US
dc.identifier.proquest2188en_US
dc.identifier.oclc659747365en_US
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