A MECHANISTIC MODEL OF BACTERIAL COLONY GROWTH AND ACTIVITY ON SOLID POROUS MEDIA.

Persistent Link:
http://hdl.handle.net/10150/185471
Title:
A MECHANISTIC MODEL OF BACTERIAL COLONY GROWTH AND ACTIVITY ON SOLID POROUS MEDIA.
Author:
WATSON, JOHN EARL.
Issue Date:
1982
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
A mechanistic model was developed, which described the growth of a bacterial colony on an agar medium. Diffusion of substrate (nutrients/oxygen) through the colony are considered. Rate of substrate use by the organisms is assumed to follow Michaelis-Menton kinetics for substrate concentrations between prescribed limits. Above and below the prescribed concentration limits, the substrate use rate is assumed constant and zero, respectively. Supply of substrate to the colony was assumed to be non-limiting. Under these conditions, the model predicted that diffusion of substrate through the colony will eventually control colony growth. It also described a slower eponential growth rate of the colony when the organisms utilized an alternate substrate for one that became deficient throughout a portion of the colony, and a constant linear growth rate when an alternate substrate was not utilized. Consistent with published literature, a mathematical description of substrate supply through the agar indicated that, under normal conditions, glucose supply through the agar to the colony would not be expected to limit colony growth before oxygen diffusion through the colony limited growth.
Type:
text; Dissertation-Reproduction (electronic)
Keywords:
Biological transport -- Mathematical models.; Bacteriology -- Cultures and culture media.; Bacterial growth -- Mathematical models.; Culture media (Biology)
Degree Name:
Ph.D.
Degree Level:
doctoral
Degree Program:
Soils and Water Engineering; Graduate College
Degree Grantor:
University of Arizona

Full metadata record

DC FieldValue Language
dc.language.isoenen_US
dc.titleA MECHANISTIC MODEL OF BACTERIAL COLONY GROWTH AND ACTIVITY ON SOLID POROUS MEDIA.en_US
dc.creatorWATSON, JOHN EARL.en_US
dc.contributor.authorWATSON, JOHN EARL.en_US
dc.date.issued1982en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractA mechanistic model was developed, which described the growth of a bacterial colony on an agar medium. Diffusion of substrate (nutrients/oxygen) through the colony are considered. Rate of substrate use by the organisms is assumed to follow Michaelis-Menton kinetics for substrate concentrations between prescribed limits. Above and below the prescribed concentration limits, the substrate use rate is assumed constant and zero, respectively. Supply of substrate to the colony was assumed to be non-limiting. Under these conditions, the model predicted that diffusion of substrate through the colony will eventually control colony growth. It also described a slower eponential growth rate of the colony when the organisms utilized an alternate substrate for one that became deficient throughout a portion of the colony, and a constant linear growth rate when an alternate substrate was not utilized. Consistent with published literature, a mathematical description of substrate supply through the agar indicated that, under normal conditions, glucose supply through the agar to the colony would not be expected to limit colony growth before oxygen diffusion through the colony limited growth.en_US
dc.typetexten_US
dc.typeDissertation-Reproduction (electronic)en_US
dc.subjectBiological transport -- Mathematical models.en_US
dc.subjectBacteriology -- Cultures and culture media.en_US
dc.subjectBacterial growth -- Mathematical models.en_US
dc.subjectCulture media (Biology)en_US
thesis.degree.namePh.D.en_US
thesis.degree.leveldoctoralen_US
thesis.degree.disciplineSoils and Water Engineeringen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.identifier.proquest8309041en_US
dc.identifier.oclc688320212en_US
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