MEMORY FUNCTIONING IN PARKINSON'S DISEASE: THE EFFECT OF AGE OF ONSET ON HIGH SPEED MEMORY SCANNING.

Persistent Link:
http://hdl.handle.net/10150/184223
Title:
MEMORY FUNCTIONING IN PARKINSON'S DISEASE: THE EFFECT OF AGE OF ONSET ON HIGH SPEED MEMORY SCANNING.
Author:
STEBBINS, GLENN THURSTON, III.
Issue Date:
1987
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
A sample of 25 idiopathic Parkinson's disease subjects and 25 age and education matched elderly healthy control subjects were assessed for their speed of primary memory scanning speed using the Sternberg memory scanning paradigm. In addition, all patients were assessed for cognitive functioning as measured by the Mattis Dementia Rating Scale and the Wechsler Memory Scale. Significant differences were found between Parkinson's disease subjects and control subjects on speed of primary memory scanning, with the parkinsonian subjects performing significantly slower than the control subjects. Increased variability in the measure of memory scanning speed was noted for the parkinsonian subjects as compared to control subjects and different variables associated with increased cognitive disturbances in parkinsonian subjects were investigated as possible sources of this variability. It was found that the majority of variance could be accounted for by the parkinsonian subjects' age of symptom onset. Parkinsonian subjects who developed the disease later in life were significantly slower at primary memory scanning speed than were either parkinsonian subjects who developed the disease earlier in life, or than healthy control subjects. Cognitive variables measuring initiation and perseveration, construction and attention were found to be highly associated with increased primary memory scanning time. The relationship between these cognitive abilities and frontal lobe dysfunction is discussed. Also, the possible relationship between slowing of memory scanning and dopamine depletion is presented.
Type:
text; Dissertation-Reproduction (electronic)
Keywords:
Parkinson's disease -- Age factors.; Memory.
Degree Name:
Ph.D.
Degree Level:
doctoral
Degree Program:
Psychology; Graduate College
Degree Grantor:
University of Arizona
Advisor:
Kaszniak, Alfred

Full metadata record

DC FieldValue Language
dc.language.isoenen_US
dc.titleMEMORY FUNCTIONING IN PARKINSON'S DISEASE: THE EFFECT OF AGE OF ONSET ON HIGH SPEED MEMORY SCANNING.en_US
dc.creatorSTEBBINS, GLENN THURSTON, III.en_US
dc.contributor.authorSTEBBINS, GLENN THURSTON, III.en_US
dc.date.issued1987en_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractA sample of 25 idiopathic Parkinson's disease subjects and 25 age and education matched elderly healthy control subjects were assessed for their speed of primary memory scanning speed using the Sternberg memory scanning paradigm. In addition, all patients were assessed for cognitive functioning as measured by the Mattis Dementia Rating Scale and the Wechsler Memory Scale. Significant differences were found between Parkinson's disease subjects and control subjects on speed of primary memory scanning, with the parkinsonian subjects performing significantly slower than the control subjects. Increased variability in the measure of memory scanning speed was noted for the parkinsonian subjects as compared to control subjects and different variables associated with increased cognitive disturbances in parkinsonian subjects were investigated as possible sources of this variability. It was found that the majority of variance could be accounted for by the parkinsonian subjects' age of symptom onset. Parkinsonian subjects who developed the disease later in life were significantly slower at primary memory scanning speed than were either parkinsonian subjects who developed the disease earlier in life, or than healthy control subjects. Cognitive variables measuring initiation and perseveration, construction and attention were found to be highly associated with increased primary memory scanning time. The relationship between these cognitive abilities and frontal lobe dysfunction is discussed. Also, the possible relationship between slowing of memory scanning and dopamine depletion is presented.en_US
dc.typetexten_US
dc.typeDissertation-Reproduction (electronic)en_US
dc.subjectParkinson's disease -- Age factors.en_US
dc.subjectMemory.en_US
thesis.degree.namePh.D.en_US
thesis.degree.leveldoctoralen_US
thesis.degree.disciplinePsychologyen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorKaszniak, Alfreden_US
dc.contributor.committeememberNadel, Lynnen_US
dc.contributor.committeememberDomino, Georgeen_US
dc.contributor.committeememberAllender, Jamesen_US
dc.contributor.committeememberGreenberg, Jeffen_US
dc.identifier.proquest8727938en_US
dc.identifier.oclc699822172en_US
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