Cardiac Power Output, its Role in Defining Heart Failure for Future Mechanical Support

Persistent Link:
http://hdl.handle.net/10150/144592
Title:
Cardiac Power Output, its Role in Defining Heart Failure for Future Mechanical Support
Author:
Garcia, Jorge
Issue Date:
2011
Publisher:
The University of Arizona.
Rights:
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
Abstract:
Cardiac Power Output (CPO) has shown to effectively indentify declining cardiac performance in Heart Failure (HF) patients. We compared CPO to other commonly used hemodynamic parameters to establish its usefulness in determining when Mechanical Circulatory Support (MCS) is required. A retrospective study of 28 HF patients previously implanted with MCS were analyzed at 3 stages of pharmacological support. Studied subjects were separated into two categories (survived versus deceased) to compare contractile reserve differences in order to predict when complete cardiac dysfunction was met. CPO and Cardiac Power Index (CPI) were the two hemodynamic parameters that identified remaining contractile reserve in the declining heart (p < 0.05). Other commonly used hemodynamic parameters failed to provide information that can detect the need for MCS. Patients who decreased below 0.70 (Watts) had higher incidences of mortality and /or morbidity. Clinicians who cannot medically manage HF patients above 0.70 W may consider MCS as an alternative treatment to retain hemodynamic stability.
Type:
Electronic Thesis; text
Keywords:
Cardiac Power Output
Degree Name:
M.S.
Degree Level:
masters
Degree Program:
Graduate College; Medical Pharmacology
Degree Grantor:
University of Arizona
Advisor:
Larson, Douglas F.

Full metadata record

DC FieldValue Language
dc.language.isoenen_US
dc.titleCardiac Power Output, its Role in Defining Heart Failure for Future Mechanical Supporten_US
dc.creatorGarcia, Jorgeen_US
dc.contributor.authorGarcia, Jorgeen_US
dc.date.issued2011-
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.en_US
dc.description.abstractCardiac Power Output (CPO) has shown to effectively indentify declining cardiac performance in Heart Failure (HF) patients. We compared CPO to other commonly used hemodynamic parameters to establish its usefulness in determining when Mechanical Circulatory Support (MCS) is required. A retrospective study of 28 HF patients previously implanted with MCS were analyzed at 3 stages of pharmacological support. Studied subjects were separated into two categories (survived versus deceased) to compare contractile reserve differences in order to predict when complete cardiac dysfunction was met. CPO and Cardiac Power Index (CPI) were the two hemodynamic parameters that identified remaining contractile reserve in the declining heart (p < 0.05). Other commonly used hemodynamic parameters failed to provide information that can detect the need for MCS. Patients who decreased below 0.70 (Watts) had higher incidences of mortality and /or morbidity. Clinicians who cannot medically manage HF patients above 0.70 W may consider MCS as an alternative treatment to retain hemodynamic stability.en_US
dc.typeElectronic Thesisen_US
dc.typetexten_US
dc.subjectCardiac Power Outputen_US
thesis.degree.nameM.S.en_US
thesis.degree.levelmastersen_US
thesis.degree.disciplineGraduate Collegeen_US
thesis.degree.disciplineMedical Pharmacologyen_US
thesis.degree.grantorUniversity of Arizonaen_US
dc.contributor.advisorLarson, Douglas F.en_US
dc.contributor.committeememberSmith, Richard G.en_US
dc.contributor.committeememberPalmer, John D.en_US
dc.identifier.proquest11613-
dc.identifier.oclc752261472-
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